ArticleJournal of virology2002
Characterization of an enteropathogenic bovine calicivirus representing a potentially new calicivirus genus.
Article in Journal of virology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
67 citing papers in PubMed, 117 citations in OpenAlex.
- Clinical and Epidemiological Features of Calicivirus Infections in Cattle.Animals : an open access journal from MDPI · 2026Review
- Immunogenicity of a bivalent recombinant adenovirus expressing VP1 proteins of bovine norovirus and bovine nebovirus in mice and calves.BMC microbiology · 2025Article
- Molecular characteristics of bovine norovirus and nebovirus in Swedish dairy herds.Acta veterinaria Scandinavica · 2025Article
- Molecular characterization of ten viral pathogens causing calf diarrhea in Hanwoo (Bos Taurus coreanae) by next generation sequencing.BMC veterinary research · 2025Article
- Comprehensive Genomic, Mutation, Phylogenetic, and Statistical Analysis of the Monkeypox Virus Across Multiple Countries.Indian journal of microbiology · 2025Article
- Comprehensive Genomics Investigation of Neboviruses Reveals Distinct Codon Usage Patterns and Host Specificity.Microorganisms · 2024Article
- Article
- Multiple novel caliciviruses identified from stoats (Mustela erminea) in the United Kingdom.Access microbiology · 2024Article
- First Detection and Genomic Characterization of Bovine Norovirus from Yak.Pathogens (Basel, Switzerland) · 2022Article
- Literature Review: Coinfection in Young Ruminant Livestock-Pathogens (Basel, Switzerland) · 2022Review
- Genomic characterization of a nebovirus strain with a novel RdRp genotype in yaks.Archives of virology · 2021Article
- Porcine sapoviruses: Pathogenesis, epidemiology, genetic diversity, and diagnosis.Virus research · 2020Review
- First detection of neboviruses in yak (Bos grunniens) and identification of a novel neboviruses based on complete genome.Veterinary microbiology · 2019Article
- Molecular characterization of bovine noroviruses and neboviruses in Turkey: detection of recombinant strains.Archives of virology · 2019Article
- Detection and Molecular Analysis of Bovine Enteric Norovirus and Nebovirus in Turkey.Journal of veterinary research · 2018Article
- Bovine Nebovirus Interacts with a Wide Spectrum of Histo-Blood Group Antigens.Journal of virology · 2018Article
- Complete Genome Sequence of Pittsburgh Sewage-Associated Virus 1.Genome announcements · 2018Article
- Detection and Characterization of a Novel Norovirus in Bats, China.Virologica Sinica · 2018Article
- First detection of Nebovirus and Norovirus from cattle in China.Archives of virology · 2018Article
- Sequencing and molecular modeling identifies candidate members of Caliciviridae family in bats.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2016Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Bovine enteric caliciviruses (BEC) are associated with diarrhea in young calves. The BEC strains detected in Europe form a third genogroup within the genus "Norwalk-like viruses" (NLV) of the family Caliciviridae. In this report, we present sequence, clinical, and histological data characterizing a novel enteropathogenic BEC strain, NB, detected in fecal specimens from calves in the United States. The complete RNA genome of the NB virus is 7,453 bases long and is organized into two open reading frames (ORFs). ORF-1 is 2,210 amino acids long and encodes a large nonstructural polyprotein contiguous with the major capsid protein (VP1), similar to the lagoviruses and "Sapporo-like viruses" (SLV). The conserved calicivirus motifs were identified in the nonstructural proteins. ORF-2 is located at the 3' end of the genome and encodes a small basic protein (VP2) of 225 amino acids. The 5' and 3' untranslated regions are 74 and 67 bases long, respectively. Among caliciviruses, NB virus shows amino acid identities of 14.1 to 22.6% over the entire ORF-1 nonstructural-protein sequence with NLV, SLV, vesivirus, and lagovirus strains, while the overall sequence identity of the complete NB VP-1 with other caliciviruses is low, varying between 14.6 and 26.7%. Phylogenetic analysis of the complete VP1 protein, including strains from all four calicivirus genera, showed the closest grouping of NB virus to be with viruses in the genus Lagovirus, which cause liver infections and systemic hemorrhage in rabbits. In gnotobiotic calves, however, NB virus elicited only diarrhea and intestinal lesions that were most severe in the upper small intestine (duodenum and jejunum), similar to the NLV BEC strains. The tissues of major organs, including the lung, liver, kidney, and spleen, had no visible microscopic lesions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.