ArticleProceedings of the National Academy of Sciences of the United States of America2002
The heterotrimeric G protein alpha subunit acts upstream of the small GTPase Rac in disease resistance of rice.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.
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Who cites it
95 citing papers in PubMed, 269 citations in OpenAlex.
- Article
- Extra-large G proteins and their roles in plant development and responses to environmental stresses.Frontiers in plant science · 2026Review
- COPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- The role of OsRGA1 in aerenchyma formation and adventitious root growth in rice seedlings based on the U-Gompertz model.BMC plant biology · 2025Article
- RGA1 regulates grain size, rice quality and seed germination in the small and round grain mutant srg5.BMC plant biology · 2024Article
- Extra-large G proteins have extra-large effects on agronomic traits and stress tolerance in maize and rice.Trends in plant science · 2023Review
- Novel Insights into Understanding the Molecular Dialogues between Bipolaroxin and the Gα and Gβ Subunits of the Wheat Heterotrimeric G-Protein during Host-Pathogen Interaction.Antioxidants (Basel, Switzerland) · 2022Article
- Review
- A small Rho GTPase OsRacB is required for pollen germination in rice.Development, growth & differentiation · 2022Article
- The hybrid lethality of interspecific FMolecular breeding : new strategies in plant improvement · 2022Review
- Polyamine: A Potent Ameliorator for Plant Growth Response and Adaption to Abiotic Stresses Particularly the Ammonium Stress Antagonized by Urea.Frontiers in plant science · 2022Review
- Heterotrimeric G protein γ subunit DEP1 is involved in hydrogen peroxide signaling and promotes aerenchyma formation in rice roots.Plant signaling & behavior · 2021Article
- Heterotrimeric G-protein α subunit (RGA1) regulates tiller development, yield, cell wall, nitrogen response and biotic stress in rice.Scientific reports · 2021Article
- Review
- Constitutive overexpression of rice metallothionein-like gene OsMT-3a enhances growth and tolerance of Arabidopsis plants to a combination of various abiotic stresses.Journal of plant research · 2020Article
- Review
- Exploring the Brassinosteroid Signaling in Monocots Reveals Novel Components of the Pathway and Implications for Plant Breeding.International journal of molecular sciences · 2020Review
- Article
- Resistance protein Pit interacts with the GEF OsSPK1 to activate OsRac1 and trigger rice immunity.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Identification of Heterotrimeric G Protein γ3 Subunit in Rice Plasma Membrane.International journal of molecular sciences · 2018Article
35 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We used rice dwarf1 (d1) mutants lacking a single-copy Galpha gene and addressed Galpha's role in disease resistance. d1 mutants exhibited a highly reduced hypersensitive response to infection by an avirulent race of rice blast. Activation of PR gene expression in the leaves of the mutants infected with rice blast was delayed for 24 h relative to the wild type. H(2)O(2) production and PR gene expression induced by sphingolipid elicitors (SE) were strongly suppressed in d1 cell cultures. Expression of the constitutively active OsRac1, a small GTPase Rac of rice, in d1 mutants restored SE-dependent defense signaling and resistance to rice blast. Galpha mRNA was induced by an avirulent race of rice blast and SE application on the leaf. These results indicated the role of Galpha in R gene-mediated disease resistance of rice. We have proposed a model for the defense signaling of rice in which the heterotrimeric G protein functions upstream of the small GTPase OsRac1 in the early steps of signaling.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.