ArticleBritish journal of cancer2002
Population mixing and leukaemia in young people around the La Hague nuclear waste reprocessing plant.
Article in British journal of cancer, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- An examination, with a meta-analysis, of studies of childhood leukaemia in relation to population mixing.British journal of cancer · 2012Pooled it
- The Association Between Childhood Leukemia and Population Mixing: An Artifact of Focusing on Clusters?Epidemiology (Cambridge, Mass.) · 2019Article
- Temporal association between childhood leukaemia and population growth in Swiss municipalities.European journal of epidemiology · 2016Article
- Population mixing and the risk of childhood leukaemia in Switzerland: a census-based cohort study.European journal of epidemiology · 2015Article
- Childhood leukaemia, nuclear sites, and population mixing.British journal of cancer · 2011Review
- The linear no-threshold relationship is inconsistent with radiation biologic and experimental data.Radiology · 2009Article
- Childhood leukaemia and population movements in France, 1990-2003.British journal of cancer · 2008Article
- Risk factors for acute leukemia in children: a review.Environmental health perspectives · 2007Review
- Incidence of childhood leukaemia in the vicinity of nuclear sites in France, 1990-1998.British journal of cancer · 2004Article
- Review
- Population mixing and childhood leukaemia: Fallon and other US clusters.British journal of cancer · 2004Article
- Childhood leukaemia incidence and the population mixing hypothesis in US SEER data.British journal of cancer · 2004Article
- Bootstrap investigation of the stability of disease mapping of Bayesian cancer relative risk estimations.European journal of epidemiology · 2004Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In order to investigate for an association between population mixing and the occurrence of leukaemia in young people (less than 25 years), a geographical study was conducted, for the years 1979 to 1998, in Nord Cotentin (France). This area experienced between the years 1978 and 1992 a major influx of workers for the construction of a nuclear power station and a new nuclear waste reprocessing unit. A population mixing index was defined on the basis of the number of workers born outside the French department of 'La Manche' and living in each 'commune', the basic geographical unit under study. The analyses were done with indirect standardisation and Poisson regression model allowing or not for extra-Poisson variation. Urban 'communes' were considered as the reference population. The Incidence Rate Ratio was 2.7 in rural 'communes' belonging to the highest tertile of population mixing (95% Bayesian credible interval, 95%BCI=1.2-5.9). A positive trend was observed among rural strata with increasing population mixing index (IRR for trend=1.4, 95%BCI=1.1-1.8). The risk became stronger for Acute Lymphoblastic Leukaemia in children 1-6 years old in the highest tertile of population mixing (IRR=5.5, 95%BCI=1.4-23.3). These findings provide further support for a possible infective basis of childhood leukaemia.
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