ArticleInfection and immunity2002
Requirement for tumor necrosis factor receptor 2 expression on vascular cells to induce experimental cerebral malaria.
Article in Infection and immunity, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 32 citations in OpenAlex.
- Myeloid expression of the AP-1 transcription factor JUNB modulates outcomes of type 1 and type 2 parasitic infections.Parasite immunology · 2015Article
- Evidence of promiscuous endothelial binding by Plasmodium falciparum-infected erythrocytes.Cellular microbiology · 2014Article
- Host resistance to malaria: using mouse models to explore the host response.Mammalian genome : official journal of the International Mammalian Genome Society · 2011Review
- Protein kinase C-theta is required for development of experimental cerebral malaria.The American journal of pathology · 2011Article
- Both functional LTbeta receptor and TNF receptor 2 are required for the development of experimental cerebral malaria.PloS one · 2008Article
- Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children.Malaria journal · 2007Article
- Impairment of functional capillary density but not oxygen delivery in the hamster window chamber during severe experimental malaria.The American journal of pathology · 2007Article
- The intriguing biology of the tumour necrosis factor/tumour necrosis factor receptor superfamily: players, rules and the games.Immunology · 2005Review
- Pathogenic role of P-selectin in experimental cerebral malaria: importance of the endothelial compartment.The American journal of pathology · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Using tumor necrosis factor receptor type 2 (TNFR2)-deficient mice and generating bone marrow chimeras which express TNFR2 on either hematopoietic or nonhematopoietic cells, we demonstrated the requirement for TNFR2 expression on tissue cells to induce lethal cerebral malaria. Thus, TNFR2 on the brain vasculature mediates tumor necrosis factor-induced neurovascular lesions in experimental cerebral malaria.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.