ArticlePharmacy world & science : PWS2002
Anti-asthmatic drugs and dosage forms in children: a cross-sectional study.
Article in Pharmacy world & science : PWS, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.
- Inter-country variations in anti-asthmatic drug prescriptions for children. Systematic review of studies published during the 2000-2009 period.European journal of clinical pharmacology · 2010Pooled it
- Anti-asthma medication prescribing to children in the Lombardy Region of Italy: chronic versus new users.BMC pulmonary medicine · 2011Article
- Prescription of respiratory medication without an asthma diagnosis in children: a population based study.BMC health services research · 2008Article
- Prescribed doses of inhaled steroids in Dutch children: too little or too much, for too short a time.British journal of clinical pharmacology · 2006Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo describe the choice of drugs as well as the dosage forms of anti-asthmatic drugs in children with regard to different age groups.
methodsCross-sectional study based on computerized pharmacy dispensing records of 1999 for children aged 0-16 years in the north of the Netherlands. All children were selected and divided in the following age groups: 0-1, 2-5, 6-11 and 12-16-year-olds.
resultsInhaled beta 2-agonists and inhaled corticosteroids were the most widely used anti-asthmatic drugs in all age groups (respectively 59 and 58 users per 100 anti-asthmatic using 0-16 year-olds). Cromones were rarely used. Up to four years of age the use of treatment with aerosol inhalers increased simultaneously with a decrease of oral dosage forms. The use of dry powder inhalers started at the age of approximately 4 years old and increased to about 85% of the users at the age of 11, with the strongest increase around the age of 6 and 7.
conclusionThe choice of drugs and dosage forms corresponds with what might be expected based on guidelines for the treatment of asthma in children, except for the high use of deptropine in the youngest age group. Anti-asthmatic drugs for preventive treatment are used so frequently without beta 2-agonists that questions about possible overtreatment need to be raised.
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