ArticleThe Plant cell2002
ANTHOCYANIN1 of petunia controls pigment synthesis, vacuolar pH, and seed coat development by genetically distinct mechanisms.
Article in The Plant cell, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.
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85 citing papers in PubMed, 280 citations in OpenAlex.
- R2R3-MYB transcription factor MYB113 specifically regulates anthocyanin accumulation in Lycium ruthenicum.Plant cell reports · 2026Article
- Overexpression of a Tonoplast Malate Transporter Gene Leads to Enhanced Anthocyanin Biosynthesis in Apple.Plant biotechnology journal · 2026Article
- Three bilberry bHLHs of subgroup IIIf play divergent roles in fruit anthocyanin and flavonoid biosynthesis.Scientific reports · 2025Article
- Metabolomics and Transcriptomics Jointly Explore the Mechanism of Pod Color Variation in Purple Pod Pea.Current issues in molecular biology · 2025Article
- Allelic variation of BBX24 is a dominant determinant controlling red coloration and dwarfism in pear.Plant biotechnology journal · 2024Article
- The lemon genome and DNA methylome unveil epigenetic regulation of citric acid biosynthesis during fruit development.Horticulture research · 2024Article
- Differentially Expressed Genes Related to Isoflavone Biosynthesis in a Soybean Mutant Revealed by a Comparative Transcriptomic Analysis.Plants (Basel, Switzerland) · 2024Article
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- Pangenome analysis provides insight into the evolution of the orange subfamily and a key gene for citric acid accumulation in citrus fruits.Nature genetics · 2023Article
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- Vaccinium as a comparative system for understanding of complex flavonoid accumulation profiles and regulation in fruit.Plant physiology · 2023Article
- A novel R2R3-MYB transcription factor FaMYB5 positively regulates anthocyanin and proanthocyanidin biosynthesis in cultivated strawberries (Fragaria × ananassa).Plant biotechnology journal · 2023Article
- Transcriptional profiling of long noncoding RNAs associated with flower color formation in Ipomoea nil.Planta · 2023Article
- Transcriptional networks orchestrating red and pink testa color in peanut.BMC plant biology · 2023Article
- Establishing Physalis as a Solanaceae model system enables genetic reevaluation of the inflated calyx syndrome.The Plant cell · 2023Article
- Integrated transcriptomics and metabolomics analysis provide insight into anthocyanin biosynthesis for sepal color formation inFrontiers in plant science · 2023Article
- Flavonoids - flowers, fruit, forage and the future.Journal of the Royal Society of New Zealand · 2023Review
- Dimerization of PtrMYB074 and PtrWRKY19 mediates transcriptional activation of PtrbHLH186 for secondary xylem development in Populus trichocarpa.The New phytologist · 2022Article
- A large deletion at the cortex locus eliminates butterfly wing patterning.G3 (Bethesda, Md.) · 2022Article
25 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ANTHOCYANIN1 (AN1) of petunia is a transcription factor of the basic helix-loop-helix (bHLH) family that is required for the synthesis of anthocyanin pigments. Here, we show that AN1 controls additional aspects of cell differentiation: the acidification of vacuoles in petal cells, and the size and morphology of cells in the seed coat epidermis. We identified an1 alleles, formerly known as ph6, that sustain anthocyanin synthesis but not vacuolar acidification and seed coat morphogenesis. These alleles express truncated proteins lacking the C-terminal half of AN1, including the bHLH domain, at an approximately 30-fold higher level than wild-type AN1. An allelic series in which one, two, or three amino acids were inserted into the bHLH domain indicated that this domain is required for both anthocyanin synthesis and vacuolar acidification. These findings show that AN1 controls more aspects of epidermal cell differentiation than previously thought through partially separable domains.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.