ArticleJournal of human hypertension2002
Pulse pressure and coronary mortality in elderly men and women from general population.
Article in Journal of human hypertension, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Brachial pulse pressure and cardiovascular or all-cause mortality in the general population: a meta-analysis of prospective observational studies.Journal of clinical hypertension (Greenwich, Conn.) · 2014Pooled it
- Effects of candesartan in hypertensive patients with type 2 diabetes mellitus on inflammatory parameters and their relationship to pulse pressure.Cardiovascular diabetology · 2012Trial
- Sex differences in blood pressure and hypertension through adulthood.Clinical kidney journal · 2026Article
- Exploring the relationship between admission pulse pressure and clinical features in patients with spontaneous supratentorial intracerebral hemorrhage.Neurosurgical review · 2023Article
- Carotid Artery Stiffness in Metabolic Syndrome: Sex Differences.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Article
- Sex Difference in the Association Between Brachial Pulse Pressure and Coronary Artery Disease: The Korean Women's Chest Pain Registry (KoROSE).Journal of clinical hypertension (Greenwich, Conn.) · 2017Article
- High pulse pressure is not associated with abnormal activation of the renin-angiotensin-aldosterone system in repaired aortic coarctation.Journal of human hypertension · 2015Observational
- The ROVIGO study (risk of vascular complications: impact of genetics in old people): protocol, study design, and preliminary results of the initial survey : cardiovascular epidemiology in the elderly.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2015Article
- Dopamine D2R Agonist-Induced Cardiovascular Effects in Healthy Male Subjects: Potential Implications in Clinical Settings.ISRN neurology · 2014Article
- The association between blood pressure and whole blood methylmercury in a cross-sectional study among Inuit in Greenland.Environmental health : a global access science source · 2012Article
- Cognitive functions and cognitive reserve in relation to blood pressure components in a population-based cohort aged 53 to 94 years.International journal of hypertension · 2012Article
- Arterial stiffness, central hemodynamics, and cardiovascular risk in hypertension.Vascular health and risk management · 2011Review
- Antihypertensive drug therapy and blood pressure control in men and women: an international perspective.Journal of human hypertension · 2010Article
- Pulse hypertension: a new component of the metabolic syndrome in elderly women?Journal of human hypertension · 2007Article
- Sex-specific effects of ACE I/D and AGT-M235T on pulse pressure: the HyperGEN Study.Human genetics · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this work was to evaluate whether pulse pressure (PP) in elderly people is a better predictor of coronary mortality than systolic and diastolic blood pressure taken alone. For this aim, 3282 elderly subjects aged >or=65 years were studied in a population-based frame. Blood pressure was repeatedly measured and averaged; historical data, anthropometrics, blood tests and 14-year coronary mortality were recorded. Statistics included analysis of covariance, Cox analysis and bivariate vectorial analysis. Coronary mortality in women was predicted by PP (1.01 excess risk/mm Hg PP) and was significantly higher in the 3rd than in the 1st tertile of PP (relative risk 2.90); neither systolic nor diastolic pressure taken alone influenced mortality. When systolic and diastolic pressures were both entered into a Cox model, the former had a positive and the latter a negative effect on survival, confirming a prognostic role of PP. For any given level of systolic pressure, mortality was inversely associated with diastolic pressure. Finally, the mean vector representing both systolic and diastolic pressures of non-surviving women was characterised by higher systolic and lower diastolic components than in non-surviving. No significant trend of mortality in relation to either systolic blood pressure or PP was observed in men. In conclusion, the combination of systolic and diastolic pressure called PP is an independent predictor of coronary mortality in elderly females, and a better predictor than systolic or diastolic pressure alone.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.