ReviewMicrobiology and molecular biology reviews : MMBR2002
Microbial cellulose utilization: fundamentals and biotechnology.
Review in Microbiology and molecular biology reviews : MMBR, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 980 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
980 citing papers in PubMed, 4,634 citations in OpenAlex.
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- Cellulose-fueled extracellular electron transfer in termite gut microbes.Applied and environmental microbiology · 2026Article
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- Enhancing the degradation of cellulose and hemicellulose in chili pepper straw waste using Cellulomonas iranensis 7-12, which was isolated from naturally decayed chili pepper straw.BMC microbiology · 2026Article
- Impact of Biodeterioration on the Structural and Thermal Insulation Properties of Plant Fibre-Reinforced Polymer Biocomposites for Construction Applications.Materials (Basel, Switzerland) · 2026Review
- Development and characterization of a sustainable bacterial cellulose/collagen composite membrane for enhanced wound healing and tissue regeneration applications.Scientific reports · 2026Article
- A Thermostable Multifunctional GH5 Endoglucanase From Bacillus sp. for Lignocellulosic Biomass Saccharification.Biotechnology journal · 2026Article
- Characterization of crude cellulase produced by Bacillus licheniformis OE-1 from the Diyadin hot springs, Ağrı Province.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Comparing deconstruction of sugarcane bagasse by a coculture of thermophilic bacteria and a fungal cellulase system.Biotechnology for biofuels and bioproducts · 2026Article
- Enhanced petroleum hydrocarbon degradation by biosurfactant-producing bacteria from Iko River estuarine sediments, Akwa Ibom State, Nigeria.BMC ecology and evolution · 2026Article
- Adaptive evolution of electron transfer pathways inJournal of bacteriology · 2026Article
- Recent advances in biomass deconstruction, microbial conversion, artificial intelligence, and carbon capture for sustainable bioenergy.Bioresources and bioprocessing · 2026Review
- Article
- Dynamic Pareto Optimization of Consolidated Bioprocessing for Ethanol Titer, Productivity, Conversion, and Operating Severity.Bioengineering (Basel, Switzerland) · 2026Article
- Visual exoproteomics ofbioRxiv : the preprint server for biology · 2026Article
- Bio decomposition of paddy straw waste using laccase producing novel soil bacterial isolates: An eco-friendly and sustainable approach.Scientific reports · 2026Article
920 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fundamental features of microbial cellulose utilization are examined at successively higher levels of aggregation encompassing the structure and composition of cellulosic biomass, taxonomic diversity, cellulase enzyme systems, molecular biology of cellulase enzymes, physiology of cellulolytic microorganisms, ecological aspects of cellulase-degrading communities, and rate-limiting factors in nature. The methodological basis for studying microbial cellulose utilization is considered relative to quantification of cells and enzymes in the presence of solid substrates as well as apparatus and analysis for cellulose-grown continuous cultures. Quantitative description of cellulose hydrolysis is addressed with respect to adsorption of cellulase enzymes, rates of enzymatic hydrolysis, bioenergetics of microbial cellulose utilization, kinetics of microbial cellulose utilization, and contrasting features compared to soluble substrate kinetics. A biological perspective on processing cellulosic biomass is presented, including features of pretreated substrates and alternative process configurations. Organism development is considered for "consolidated bioprocessing" (CBP), in which the production of cellulolytic enzymes, hydrolysis of biomass, and fermentation of resulting sugars to desired products occur in one step. Two organism development strategies for CBP are examined: (i) improve product yield and tolerance in microorganisms able to utilize cellulose, or (ii) express a heterologous system for cellulose hydrolysis and utilization in microorganisms that exhibit high product yield and tolerance. A concluding discussion identifies unresolved issues pertaining to microbial cellulose utilization, suggests approaches by which such issues might be resolved, and contrasts a microbially oriented cellulose hydrolysis paradigm to the more conventional enzymatically oriented paradigm in both fundamental and applied contexts.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.