Evidence map›Paper›PMID 12208987›Full record

ArticleJournal of virology2002

Detection and analysis of hepatitis C virus sequences in cerebrospinal fluid.

Tomasz Laskus, Marek Radkowski, Agnieszka Bednarska, Jeffrey Wilkinson, Debra Adair, Marek Nowicki, Georgia B Nikolopoulou, Hugo Vargas, Jorge Rakela

Abstract read
In one paragraph

Article in Journal of virology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed.

  1. Neurobehavioral effects of interferon-α in patients with hepatitis-C: symptom dimensions and responsiveness to paroxetine.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2012
    Trial
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  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
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  12. Article
  13. Article
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  15. Article
  16. Hepatitis C Virus Infection in the Older Patient.Infectious disease clinics of North America · 2017
    Review
  17. Article
  18. Article
  19. Review
  20. Deep sequencing of hepatitis C virus reveals genetic compartmentalization in cerebrospinal fluid from cognitively impaired patients.Liver international : official journal of the International Association for the Study of the Liver · 2016
    Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tomasz LaskusDivision of Transplantation Medicine, Mayo Clinic, Scottsdale, Arizona 85259, USA.
Marek Radkowski
Agnieszka Bednarska
Jeffrey Wilkinson
Debra Adair
Marek Nowicki
Georgia B Nikolopoulou
Hugo Vargas
Jorge Rakela

Funding

HEPATITIS C VIRUS COINFECTION IN HIV-1 INFECTED SUBJECTSR01DA013760 · NIDA · MAYO CLINIC COLL OF MED, MAYO CLINIC AZ · PI RAKELA, JORGE X · 2000 to 2002
$1.0M
NIDA NIH HHS DA13760
6 · The paper itself

Abstract

Hepatitis C virus (HCV) sequences were detected in cerebrospinal fluid (CSF) in 8 of 13 HCV-positive patients. In four patients harboring different virus strains in serum and peripheral blood mononuclear cells (PBMC), CSF-derived virus was similar to that found in PBMC, which suggests that PBMC could carry HCV into the brain.

Indexed as

5' Untranslated RegionsAdultBase SequenceCerebrospinal FluidFemaleHepacivirusHumansMaleMiddle AgedMolecular Sequence DataReverse Transcriptase Polymerase Chain ReactionRNA, Viral5' Untranslated RegionsRNA, Viral

Identifiers

PMID12208987
PMCPMC136534

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.