ArticleJournal of clinical pathology2002
Increase in alcohol related deaths: is hepatitis C a factor?
Article in Journal of clinical pathology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 20 citations in OpenAlex.
- Hepatitis C infection substantially reduces survival of alcohol-dependent patients.Clinical epidemiology · 2018Article
- Treatment options for alcoholic and non-alcoholic fatty liver disease: A review.World journal of gastroenterology · 2017Review
- Alcoholic liver disease and hepatitis C virus infection.World journal of gastroenterology · 2016Review
- Alcoholic hepatitis and concomitant hepatitis C virus infection.World journal of gastroenterology · 2014Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo evaluate recent trends in alcohol related deaths in the UK and to consider possible causative factors.
designObservational retrospective study of the database of the Office for National Statistics, alcohol consumption data reported by the General Household Survey, and other published data.
settingEngland, 1993-9.
resultsDeaths for each million of the population from alcohol related illness increased by 59% in men and 40% in women over the years 1993 to 1999. One subgroup of alcohol related deaths, ICD 571.3 (alcoholic liver damage unspecified), showed a 243% increase in men aged 40 to 49 years over the same period. Figures for younger men, and women in all age groups, showed less pronounced increases. There has been no associated rise in alcohol intake. There has been an increase in the incidence of hepatitis C virus (HCV) infection in recent years, and alcohol consumption in HCV positive individuals accelerates the progression to cirrhosis. Circumstantial evidence links the rise in HCV infection to the use of illicit drugs in the 1970s and 1980s, among those currently aged 40 to 59 years.
conclusionsThe recent increase in alcohol related deaths cannot be solely explained by a change in drinking habits. It is suggested that this probably results from the rapid progression of alcoholic cirrhosis in people who have acquired HCV infection through intravenous drug use. Alcohol consumption in HCV positive individuals is firmly linked with a poor outcome.
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Registered trials
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