Evidence map›Paper›PMID 12194905›Full record

ReviewEnvironmental health perspectives2002

A status report on chronic fatigue syndrome.

Benjamin H Natelson, Gudrun Lange

Abstract readReview
In one paragraph

Review in Environmental health perspectives, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Phenylephrine alters phase synchronization between cerebral blood velocity and blood pressure in ME/CFS with orthostatic intolerance.American journal of physiology. Regulatory, integrative and comparative physiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Benjamin H NatelsonDepartment of Neurosciences, Chronic Fatigue Syndrome Cooperative Research Center, UMDNJ, Newark, USA. bhn@njneuromed.org
Gudrun Lange

Funding

VIROLOGY ASSESSMENT OF CHRONIC FATIGUE SYNDROME PATIENTSU01AI032247 · NIAID · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI NATELSON, BENJAMIN H · 1991 to 2002
$2.4M
NIAID NIH HHS UO1-AI-32247
6 · The paper itself

Abstract

Medical history has shown that clinical disease entities or syndromes are composed of many subgroups--each with its own cause and pathogenesis. Although we cannot be sure, we expect the same outcome for chronic fatigue syndrome (CFS), a medically unexplained condition characterized by disabling fatigue accompanied by infectious, rheumatological, and neuropsychiatric symptoms. Although the ailment clearly can occur after severe infection, no convincing data exist to support an infectious (or immunologic) process in disease maintenance. Instead, data point to several possible pathophysiological processes: a covert encephalopathy, impaired physiological capability to respond to physical and mental stressors, and psychological factors related to concerns about effort exacerbating symptoms. Each of these is under intense investigation. In addition, some data do exist to indicate that environmental agents also can elicit a state of chronic fatigue. We expect data to accumulate to support the belief that CFS has multiple causes.

Indexed as

Stress, PsychologicalAdaptation, PsychologicalCognitionDizzinessEncephalitisEnvironmental PollutantsFatigue Syndrome, ChronicHumansInfectionsRisk FactorsEnvironmental Pollutants

Identifiers

PMID12194905
PMCPMC1241224

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.