ReviewCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2002
Medical genetics: 1. Clinical teratology in the age of genomics.
Review in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effects of bariatric surgery on periconception maternal health: a systematic review and meta-analysis.Human reproduction update · 2021Pooled it
- Child and maternal health outcomes following antenatal exposure to classic psychedelic substances: a systematic review.Research square · 2026Article
- Paracetamol in pregnancy: Navigating clinical uncertainty and avoiding the communication pitfalls of the "measles, mumps, and rubella" - autism controversy: A narrative review.EXCLI journal · 2026Review
- Review
- Week-by-week alcohol consumption in early pregnancy and spontaneous abortion risk: a prospective cohort study.American journal of obstetrics and gynecology · 2021Article
- Neurotropic Drugs in Pregnancy and Lactation from the Point of View of the Clinical Teratologist.Current neuropharmacology · 2021Article
- Identifying pattern in global developmental delay children: A retrospective study at King Fahad specialist hospital, Dammam (Saudi Arabia).Pediatric reports · 2019Article
- Zika Virus Infection in Pregnancy: Maternal, Fetal, and Neonatal Considerations.The Journal of infectious diseases · 2017Review
- Post-licensure safety surveillance for human papillomavirus-16/18-AS04-adjuvanted vaccine: more than 4 years of experience.Pharmacoepidemiology and drug safety · 2014Review
- Ascorbic acid reverses valproic acid-induced inhibition of hoxa2 and maintains glutathione homeostasis in mouse embryos in culture.Cellular and molecular neurobiology · 2010Article
- Effect of anti-epileptic drugs in pregnancy and teratogenesis.Indian journal of clinical biochemistry : IJCB · 2008Article
- Teratogenicity of antiepileptic medications.Seminars in neurology · 2008Review
- Accutane (isotretinoin) and psychiatric adverse effects.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2003Review
- The very youngest science.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2002Article
Corrections and comments
- Commented on by
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Teratogenic exposures are those that can cause an embryo or fetus to develop abnormally. Several factors determine whether an agent is teratogenic, including the gestational timing of the exposure, as well as the dose, route and nature of the agent itself. We review the general concepts of teratogenesis, as well as known genetic susceptibilities to teratogenic effects, with a special focus on antiepileptic drugs. We discuss general principles of risk counselling and risk reduction, and we describe several long-known teratogens, as well as several exposures recognized only recently to have teratogenic potential.
Indexed as
Identifiers
12186175PMC117475What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.