ArticleInfection and immunity2002
Differential expression of the p44 gene family in the agent of human granulocytic ehrlichiosis.
Article in Infection and immunity, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 35 citations in OpenAlex.
- Haematology, serum biochemistry, innate and adaptive immune system responses to blood pathogen infections in cattle: A review.Parasitology research · 2026Review
- Global Transcription Profiles ofFrontiers in veterinary science · 2020Article
- Differential Susceptibility of Male Versus Female Laboratory Mice toTropical medicine and infectious disease · 2018Article
- Adaptive immunity to Anaplasma pathogens and immune dysregulation: implications for bacterial persistence.Comparative immunology, microbiology and infectious diseases · 2012Review
- Proteomic analysis of Anaplasma phagocytophilum during infection of human myeloid cells identifies a protein that is pronouncedly upregulated on the infectious dense-cored cell.Infection and immunity · 2011Article
- Anaplasma phagocytophilum induces Ixodes scapularis ticks to express an antifreeze glycoprotein gene that enhances their survival in the cold.The Journal of clinical investigation · 2010Article
- Human ehrlichiosis and anaplasmosis.Clinics in laboratory medicine · 2010Review
- Differential expression and glycosylation of anaplasma phagocytophilum major surface protein 2 paralogs during cultivation in sialyl Lewis x-deficient host cells.Infection and immunity · 2009Article
- Defining the immune response to Ehrlichia species using murine models.Veterinary parasitology · 2008Article
- Anaplasma phagocytophilum MSP2(P44)-18 predominates and is modified into multiple isoforms in human myeloid cells.Infection and immunity · 2008Article
- Outer membrane protein sequence variation in lambs experimentally infected with Anaplasma phagocytophilum.Infection and immunity · 2008Article
- An Ixodes scapularis protein required for survival of Anaplasma phagocytophilum in tick salivary glands.The Journal of experimental medicine · 2006Article
- Two monoclonal antibodies with defined epitopes of P44 major surface proteins neutralize Anaplasma phagocytophilum by distinct mechanisms.Infection and immunity · 2006Article
- Rapid sequential changeover of expressed p44 genes during the acute phase of Anaplasma phagocytophilum infection in horses.Infection and immunity · 2004Article
- Polymorphism and transcription at the p44-1/p44-18 genomic locus in Anaplasma phagocytophilum strains from diverse geographic regions.Infection and immunity · 2004Article
- Anaplasma phagocytophilum has a functional msp2 gene that is distinct from p44.Infection and immunity · 2004Article
- Sequence analysis of p44 homologs expressed by Anaplasma phagocytophilum in infected ticks feeding on naive hosts and in mice infected by tick attachment.Infection and immunity · 2004Article
- Restricted changes in major surface protein-2 (msp2) transcription after prolonged in vitro passage of Anaplasma phagocytophilum.BMC microbiology · 2004Article
- Mechanisms of variable p44 expression by Anaplasma phagocytophilum.Infection and immunity · 2003Article
- Serotyping isolates of Anaplasma phagocytophilum by using monoclonal antibodies.Clinical and diagnostic laboratory immunology · 2003Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Using reverse transcription-PCR targeting of the p44 genes of the agent of human granulocytic ehrlichiosis (HGE) with primers flanking the hypervariable region, we show differential expression in a murine model of HGE infection and during tick transmission. The p44 genes were differentially expressed in salivary glands of infected nymphal ticks removed during transmission feeding but not in nonfeeding infected ticks. Similarly, the p44 genes were differentially expressed in infected C3H mice, in SCID mice, and in cultured HGE bacteria. Thus, differential p44 expression exists in vivo and in vitro and could provide a basis for antigenic variation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.