ArticleInfection and immunity2002
Functional domain of bovine milk lactoferrin which inhibits the adherence of Streptococcus mutans cells to a salivary film.
Article in Infection and immunity, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 50 citations in OpenAlex.
- Exploring the Possible Impact of Oral Nutritional Supplements on Children's Oral Health: An In Vitro Investigation.Dentistry journal · 2024Article
- Bovine Milk and Yogurt Affect Oral Microorganisms and Biofilms In-Vitro.Oral health & preventive dentistry · 2023Article
- Prevention of Initial Bacterial Attachment by Osteopontin and Other Bioactive Milk Proteins.Biomedicines · 2022Article
- Lactoferrin: A Natural Glycoprotein Involved in Iron and Inflammatory Homeostasis.International journal of molecular sciences · 2017Review
- Health-Related Aspects of Milk Proteins.Iranian journal of pharmaceutical research : IJPR · 2016Article
- Article
- Lactoferrin and oral diseases: current status and perspective in periodontitis.Annali di stomatologia · 2011Article
- A peptide domain of bovine milk lactoferrin inhibits the interaction between streptococcal surface protein antigen and a salivary agglutinin peptide domain.Infection and immunity · 2004Article
- Analysis of the association between lactotransferrin (LTF) gene polymorphism and dental caries.Journal of applied oral science : revista FOBArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The bovine lactoferrin molecule and relatively long lactoferrin fragments containing residues 473 to 538 strongly inhibited adherence of Streptococcus mutans to saliva-coated hydroxyapatite beads. Each cysteine residue in Lf411 (residues 473 to 538) was replaced by a serine residue, and the mutants Lf411-C481S and Lf411-C532S strongly inhibited S. mutans adherence. These results suggest that the functional domain of lactoferrin that binds to a salivary film lies in residues 473 to 538 and that the region might be concealed by disulfide bond formation between Cys481 and Cys532 in the Lf411 fragment.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.