Evidence map›Paper›PMID 12183579›Full record

ArticleInfection and immunity2002

Simultaneous expression of different variant-specific surface proteins in single Giardia lamblia trophozoites during encystation.

Pedro G Carranza, Gisela Feltes, Andrea Ropolo, Silvia M C Quintana, María C Touz, Hugo D Luján

Abstract read
In one paragraph

Article in Infection and immunity, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. "Immunoinformatic Identification of T-Cell and B-Cell Epitopes FromFrontiers in cellular and infection microbiology · 2021
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pedro G CarranzaCátedra de Bioquímica y Biología Molecular, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, CP 5000 Córdoba, Argentina.
Gisela Feltes
Andrea Ropolo
Silvia M C Quintana
María C Touz
Hugo D Luján

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel variant-specific surface protein (VSP) from Giardia was identified using the monoclonal antibody 9B10, raised against purified cyst walls. VSP9B10B is preferentially induced during encystation and expressed simultaneously with other VSPs on the surface of encysting trophozoites. These results support the hypothesis that encystation and antigenic variation are processes that are mechanistically related.

Indexed as

Protozoan ProteinsAmino Acid SequenceAnimalsAntibodies, MonoclonalAntibodies, ProtozoanAntigenic VariationAntigens, ProtozoanAntigens, SurfaceBase SequenceDNA, ProtozoanGene ExpressionGenes, ProtozoanGiardia lambliaHumansMolecular Sequence DataSequence Homology, Amino AcidAntibodies, MonoclonalAntibodies, ProtozoanAntigens, ProtozoanAntigens, SurfaceDNA, ProtozoanProtozoan Proteinsvariant surface protein H7, Giardia lamblia

Identifiers

PMID12183579
PMCPMC128263

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.