ArticleInfection and immunity2002
Protection from group B streptococcal infection in neonatal mice by maternal immunization with recombinant Sip protein.
Article in Infection and immunity, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 65 citations in OpenAlex.
- Review
- Protective Effect of Nanobodies Targeting Sip Protein AgainstAnimals : an open access journal from MDPI · 2025Article
- Bioinformatics analysis to design a multi-epitope mRNA vaccine against S. agalactiae exploiting pathogenic proteins.Scientific reports · 2024Article
- Article
- CD1 and iNKT cells mediate immune responses against the GBS hemolytic lipid toxin induced by a non-toxic analog.PLoS pathogens · 2023Article
- Development and evaluation of a multi-epitope subunit vaccine against group BEmerging microbes & infections · 2022Article
- Bacterial and Host Determinants of Group B Streptococcal Vaginal Colonization and Ascending Infection in Pregnancy.Frontiers in cellular and infection microbiology · 2021Review
- IL-10-producing NK cells exacerbate sublethal Streptococcus pneumoniae infection in the lung.Translational research : the journal of laboratory and clinical medicine · 2020Article
- Mucosal Vaccination withVaccines · 2020Article
- The correlation between expression of sip protein in different serotypes of group b streptococcus and diagnosis.Heliyon · 2019Article
- Surface Structures of Group BMicrobiology spectrum · 2019Review
- Rv1288, a Two Domain, Cell Wall Anchored, Nutrient Stress Inducible Carboxyl-Esterase ofFrontiers in cellular and infection microbiology · 2018Article
- Mucosal vaccination promotes clearance of Streptococcus agalactiae vaginal colonization.Vaccine · 2017Article
- Evaluation and Selection of Appropriate Reference Genes for Real-Time Quantitative PCR Analysis of Gene Expression in Nile Tilapia (Oreochromis niloticus) during Vaccination and Infection.International journal of molecular sciences · 2015Article
- Protective activity of Streptococcus pneumoniae Spr1875 protein fragments identified using a phage displayed genomic library.PloS one · 2012Article
- Evaluation of a novel chimeric B cell epitope-based vaccine against mastitis induced by either Streptococcus agalactiae or Staphylococcus aureus in mice.Clinical and vaccine immunology : CVI · 2011Article
- Maternal immunity partially protects newborn mice against a Chlamydia trachomatis intranasal challenge.Journal of reproductive immunology · 2010Article
- Streptococcus adherence and colonization.Microbiology and molecular biology reviews : MMBR · 2009Review
- Surfome analysis as a fast track to vaccine discovery: identification of a novel protective antigen for Group B Streptococcus hypervirulent strain COH1.Molecular & cellular proteomics : MCP · 2009Article
- The antigenome: from protein subunit vaccines to antibody treatments of bacterial infections?Advances in experimental medicine and biology · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The protective potential of antibodies directed against group B streptococcus (GBS) Sip surface protein was determined by using the mouse neonatal infection model. Rabbit Sip-specific antibodies administered passively to pregnant mice protected their pups against a GBS lethal challenge. In addition, active immunization with purified recombinant Sip protein of female CD-1 mice induced the production of specific antibodies that also confer protection to the newborn pups against GBS strains of serotypes Ia/c, Ib, II, III, and V. These data confirm that Sip-specific antibodies can cross the placenta and conferred protective immunity against GBS infections.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.