ArticleJournal of assisted reproduction and genetics2002
A comparative study of Y chromosome microdeletions in infertile males from two Chinese populations.
Article in Journal of assisted reproduction and genetics, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Gene Scanning for Microdeletions in the Azoospermia Factor Region of Y-Chromosome in Infertile Men of Gujarat, India.Journal of clinical and diagnostic research : JCDR · 2017Article
- Chromosomal abnormalities and Y chromosome microdeletions in infertile men from Morocco.BMC urology · 2015Article
- High prevalence of genetic abnormalities in Middle Eastern patients with idiopathic non-obstructive azoospermia.Journal of assisted reproduction and genetics · 2013Article
- Y chromosome microdeletions in infertile men: prevalence, phenotypes and screening markers for the Indian population.Journal of assisted reproduction and genetics · 2013Article
- The low frequency of Y chromosome microdeletions in subfertile males in a Sinhalese population of Sri Lanka.Indian journal of human genetics · 2012Article
- Male infertility in China: laboratory finding for AZF microdeletions and chromosomal abnormalities in infertile men from Northeastern China.Journal of assisted reproduction and genetics · 2010Article
- Absence of microdeletions in the azoospermia-factor region of the Y-chromosome in Viennese men seeking assisted reproduction.Wiener klinische Wochenschrift · 2003Article
- Molecular analysis of the androgen receptor gene in Hong Kong Chinese infertile men.Journal of assisted reproduction and genetics · 2003Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo compare the prevalence and type of Y-microdeletions in Hong Kong and Shanghai men with severe male-factor infertility.
methodsSeven Y-linked sequence tagged site (STS) primers and seven gene-specific primers were screened in 293 infertile males (139 from Hong Kong and 154 from Shanghai) and 161 fertile men (61 from Hong Kong and 100 from Shanghai). Serum FSH, LH, and testosterone levels were also measured in these men.
resultsThe incidence of Yq microdeletions in nonobstructive azoospermic men from Hong Kong (8.5%) and Shanghai (6%) was similar. Yq microdeletions were observed in severe oligospermic patients (8.5%) from Hong Kong but not from Shanghai. Among the 9 Hong Kong men with Y-microdeletions, 8 had AZFc deletion and one had AZFb deletion. In contrast, 6 of 9 men from Shanghai with Y-microdeletions had AZFb deletion. The incidence of AZFb deletion among Y-microdeleted men was statistically different between the two populations. Two of the men with AZFb deletion also had AZFa and AZFc deletions.
conclusionsRegional variations in the type of Y-microdeletion existed between Hong Kong and Shanghai infertile males.
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