ArticleProceedings of the National Academy of Sciences of the United States of America2002
Global analysis of the Deinococcus radiodurans proteome by using accurate mass tags.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
114 citing papers in PubMed, 390 citations in OpenAlex.
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- Improved Detection of Differentially Abundant Proteins through FDR-Control of Peptide-Identity-Propagation.Journal of proteome research · 2025Article
- The DR2416/DR2415 two-component system is responsible for the radioresistance of Deinococcus radiodurans.Antonie van Leeuwenhoek · 2025Article
- Quality Control in the Mass Spectrometry Proteomics Core: A Practical Primer.Journal of biomolecular techniques : JBT · 2024Article
- Challenges and Opportunities for Single-cell Computational Proteomics.Molecular & cellular proteomics : MCP · 2023Review
- iTRAQ-based proteomic analysis of Deinococcus radiodurans in response toBMC microbiology · 2022Article
- Thiol Reductases inAntioxidants (Basel, Switzerland) · 2022Review
- A small RNA regulates pprM, a modulator of pleiotropic proteins promoting DNA repair, in Deinococcus radiodurans under ionizing radiation.Scientific reports · 2021Article
- Proteomic Analyses of Vitreous in Proliferative Diabetic Retinopathy: Prior Studies and Future Outlook.Journal of clinical medicine · 2021Review
- DRJAMM Is Involved in the Oxidative Resistance inFrontiers in microbiology · 2021Article
- Protein structure, amino acid composition and sequence determine proteome vulnerability to oxidation-induced damage.The EMBO journal · 2020Article
- Ionizing Radiation-induced Proteomic Oxidation inMolecular & cellular proteomics : MCP · 2020Article
- Nitrogen Source Governs Community Carbon Metabolism in a Model Hypersaline Benthic Phototrophic Biofilm.mSystems · 2020Article
- Comparative Proteomics Analysis Reveals New Features of the Oxidative Stress Response in the Polyextremophilic BacteriumMicroorganisms · 2020Article
- Signal Recognition Particle RNA Contributes to Oxidative Stress Response inFrontiers in microbiology · 2020Article
- Growth phase proteomics of the heterotrophic marine bacterium Ruegeria pomeroyi.Scientific data · 2019Article
- Specialized proteomic responses and an ancient photoprotection mechanism sustain marine green algal growth during phosphate limitation.Nature microbiology · 2018Article
- PprM is necessary for up-regulation of katE1, encoding the major catalase of Deinococcus radiodurans, under unstressed culture conditions.Journal of microbiology (Seoul, Korea) · 2016Article
- Evidence-based green algal genomics reveals marine diversity and ancestral characteristics of land plants.BMC genomics · 2016Article
- Comparative Proteomic Analysis of Desulfotomaculum reducens MI-1: Insights into the Metabolic Versatility of a Gram-Positive Sulfate- and Metal-Reducing Bacterium.Frontiers in microbiology · 2016Article
54 more citing papers are in PubMed but not listed here.
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Authors and funding
22 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding biological systems and the roles of their constituents is facilitated by the ability to make quantitative, sensitive, and comprehensive measurements of how their proteome changes, e.g., in response to environmental perturbations. To this end, we have developed a high-throughput methodology to characterize an organism's dynamic proteome based on the combination of global enzymatic digestion, high-resolution liquid chromatographic separations, and analysis by Fourier transform ion cyclotron resonance mass spectrometry. The peptides produced serve as accurate mass tags for the proteins and have been used to identify with high confidence >61% of the predicted proteome for the ionizing radiation-resistant bacterium Deinococcus radiodurans. This fraction represents the broadest proteome coverage for any organism to date and includes 715 proteins previously annotated as either hypothetical or conserved hypothetical.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.