ArticleGenome research2002
Parallel identification of new genes in Saccharomyces cerevisiae.
Article in Genome research, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Proteogenomic Identification of Annotated and Novel smORFs Via Microprotein Enrichment.Methods in molecular biology (Clifton, N.J.) · 2026Article
- A vast evolutionarily transient translatome contributes to phenotype and fitness.Cell systems · 2023Article
- Uncovering de novo gene birth in yeast using deep transcriptomics.Nature communications · 2021Article
- Proteogenomics produces comprehensive and highly accurate protein-coding gene annotation in a complete genome assembly of Malassezia sympodialis.Nucleic acids research · 2017Article
- Article
- Proteogenomic analysis of pathogenic yeast Cryptococcus neoformans using high resolution mass spectrometry.Clinical proteomics · 2014Article
- Deep coverage of the Escherichia coli proteome enables the assessment of false discovery rates in simple proteogenomic experiments.Molecular & cellular proteomics : MCP · 2013Article
- Protein analysis by shotgun/bottom-up proteomics.Chemical reviews · 2013Review
- Gapped spectral dictionaries and their applications for database searches of tandem mass spectra.Molecular & cellular proteomics : MCP · 2011Article
- Article
- Proteogenomics to discover the full coding content of genomes: a computational perspective.Journal of proteomics · 2010Review
- Top-down proteomics reveals novel protein forms expressed in Methanosarcina acetivorans.Journal of the American Society for Mass Spectrometry · 2009Article
- Ortho-proteogenomics: multiple proteomes investigation through orthology and a new MS-based protocol.Genome research · 2009Article
- Novel low abundance and transient RNAs in yeast revealed by tiling microarrays and ultra high-throughput sequencing are not conserved across closely related yeast species.PLoS genetics · 2008Article
- Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility.Nature chemical biology · 2008Article
- Evidence-based annotation of the malaria parasite's genome using comparative expression profiling.PloS one · 2008Article
- Whole proteome analysis of post-translational modifications: applications of mass-spectrometry for proteogenomic annotation.Genome research · 2007Article
- Why are there still over 1000 uncharacterized yeast genes?Genetics · 2007Review
- A large-scale full-length cDNA analysis to explore the budding yeast transcriptome.Proceedings of the National Academy of Sciences of the United States of America · 2006Article
- Saccharomyces cerevisiae S288C genome annotation: a working hypothesis.Yeast (Chichester, England) · 2006Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Short open reading frames (ORFs) occur frequently in primary genome sequence. Distinguishing bona fide small genes from the tens of thousands of short ORFs is one of the most challenging aspects of genome annotation. Direct experimental evidence is often required. Here we use a combination of expression profiling and mass spectrometry to verify the independent transcription of 138 and the translation of 50 previously nonannotated genes in the Saccharomyces cerevisiae genome. Through combined evidence, we propose the addition of 62 new genes to the genome and provide experimental support for the inclusion of 10 previously identified genes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.