ArticleGut2002
Intraductal papillary and mucinous pancreatic tumour: a new extracolonic tumour in familial adenomatous polyposis.
Article in Gut, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 99 citations in OpenAlex.
- Cronkhite-Canada syndrome: An elusive gastrointestinal disorder with multisystem involvement-pathogenesis, diagnosis, and therapeutic strategies.World journal of gastrointestinal pathophysiology · 2026Review
- Advancements in Early Detection and Screening Strategies for Pancreatic Cancer: From Genetic Susceptibility to Novel Biomarkers.Journal of clinical medicine · 2024Review
- Article
- Synchronous manifestation of colorectal cancer and intraductal papillary mucinous neoplasms.World journal of clinical cases · 2023Review
- Intraductal Papillary Mucinous Neoplasms in Hereditary Cancer Syndromes.Biomedicines · 2022Review
- Intraductal Papillary Mucinous Neoplasms of the Pancreas: A Review of Their Genetic Characteristics and Mouse Models.Cancers · 2021Review
- Solid-pseudopapillary neoplasm of the pancreas in a patient with familial adenomatous polyposis: a case report.Surgical case reports · 2021Article
- Effect of Adenomatous Polyposis Coli Loss on Tumorigenic Potential in Pancreatic Ductal Adenocarcinoma.Cells · 2019Article
- Early Detection of Pancreatic Cancer: Opportunities and Challenges.Gastroenterology · 2019Review
- Pancreatic intraductal papillary mucinous neoplasm in a patient with Lynch syndrome.World journal of gastroenterology · 2015Article
- Natural History and Management of Intraductal Papillary Mucinous Neoplasms: Current Evidence.Viszeralmedizin · 2015Review
- Cyst Features and Risk of Malignancy in Intraductal Papillary Mucinous Neoplasms of the Pancreas: Imaging and Pathology.Viszeralmedizin · 2015Review
- Rare combination of familial adenomatous polyposis and gallbladder polyps.World journal of gastroenterology · 2014Article
- Pancreatic ductal adenocarcinoma: risk factors, screening, and early detection.World journal of gastroenterology · 2014Review
- Genetic predisposition to pancreatic cancer.World journal of gastroenterology · 2014Review
- Endoscopic ultrasonography for surveillance of individuals at high risk for pancreatic cancer.World journal of gastrointestinal endoscopy · 2014Review
- Familial pancreatic cancer--status quo.International journal of colorectal disease · 2014Review
- Carcinogenesis of pancreatic adenocarcinoma: precursor lesions.International journal of molecular sciences · 2013Review
- Intraductal papillary mucinous neoplasms of the pancreas: is the puzzle solved?Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2013Review
- Pancreatic cystic neoplasms: a review of preoperative diagnosis and management.Journal of Zhejiang University. Science. B · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Familial adenomatous polyposis (FAP) is characterised by the development of numerous colorectal adenomatous polyps. Other extracolonic benign or malignant lesions have been reported previously in association with FAP but precancerous lesions in the pancreas have never been described. We report the first case of intraductal papillary and mucinous pancreatic tumour (IPMT) in a patient with FAP. A 48 year old man with a well documented past history of FAP was admitted for epigastric pain, weight loss, and new onset diabetes mellitus. Spiral computed tomography scan revealed a large tumour in the pancreatic head with upstream main pancreatic duct dilatation. Endoscopic ultrasonography confirmed these data. Mucous secretion was seen at duodenoscopy and a lesion in the main pancreatic duct was confirmed by retrograde pancreatography. The patient underwent a pancreaticoduodenectomy for suspected IPMT. Histological examination of the resected specimen confirmed an IPMT with in situ carcinoma. Twelve months after resection, the patient remained free of tumour relapse. Genetic analysis showed loss of the wild allele of the adenomatous polyposis coli gene in IPMT, causing inactivation of both alleles and demonstrating that IPMT was not incidental in this patient. IPMT should be included in the extracolonic localisation of FAP.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.