ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2002
Follow-up, treatment, and reinfection rates among asymptomatic chlamydia trachomatis cases in general practice.
Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Chlamydia trachomatis orchestrates multifaceted host cell manipulation for immune evasion.Communications biology · 2026Review
- Bacterial Vaginosis and Spontaneous Clearance of Chlamydia trachomatis in the Longitudinal Study of Vaginal Flora.The Journal of infectious diseases · 2023Article
- TLR2, TLR4 and TLR9 genotypes and haplotypes in the susceptibility to and clinical course of Chlamydia trachomatis infections in Dutch women.Pathogens and disease · 2016Article
- Modelling the impact of chlamydia screening on the transmission of HIV among men who have sex with men.BMC infectious diseases · 2013Article
- Efficacy of an immune modulator in experimental Chlamydia trachomatis infection of the female genital tract.Infectious diseases in obstetrics and gynecology · 2006Article
- Acquired homotypic and heterotypic immunity against oculogenital Chlamydia trachomatis serovars following female genital tract infection in mice.BMC infectious diseases · 2005Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAdequate treatment and follow-up of patients is essential to the success of a screening programme for Chlamydia trachomatis. There has been a lack of data on follow-up, confirmation of infections, and reinfection rates among asymptomatic patients in general practice.
aim7b study the rates of diagnostic confirmation of C trachomatis infection, successful treatment, and reinfection one year after cases were detected in a screening programme for asymptomatic infections. DESIGN OF STUDY: Prospective cohort study
settingFifteen general practices in Amsterdam, The Netherlands.
methodOne hundred and twenty-four patients with asymptomatic C trachomatis infections were requested to provide a cervical or urethral swab and a urine specimen, for the purpose of diagnostic confirmation before being treated. One year after the first screening, all of the patients were invited for a second screening. All samples were tested using the ligase chain reaction (Abbott Laboratories, Chicago, USA).
resultsOut of 124 patients, 110 (89%) attended the scheduled appointment for diagnostic confirmation and treatment; 92 (84%) of them were confirmed to be positive and received treatment. At the second screening a year later, none of the 56 patients who had received treatment and who had been screened a second time were reinfected.
conclusionNo asymptomatic patients werefound to have reinfections with C trachomatis one year after diagnostic confirmation and treatment. This underlines the effectiveness of the screening and treatment strategy
Indexed as
Identifiers
12171219PMC1314379What OpenQuestion holds
Registered trials
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