ArticleThe EMBO journal2002
Antagonistic regulation of flowering-time gene SOC1 by CONSTANS and FLC via separate promoter motifs.
Article in The EMBO journal, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 193 papers.
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193 citing papers in PubMed.
- FLC genes control flowering time to varying degrees in a Brassica napus spring cultivar.Plant molecular biology · 2026Article
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- Transcriptomic insights into gibberellin-3-mediated regulation of bud dormancy and metabolic transition in pitaya (Hylocereus polyrhizus).Plant cell reports · 2025Article
- Seasons and shape: inflorescences from autumn to summer.Journal of experimental botany · 2025Review
- Induction of flowering with a photoperiod extension coupled with gibberellic acid treatment: physiological and molecular insights in Allium species.BMC plant biology · 2025Article
- Soybean GmWRKY44 transcription factor activates SOC1 and LFY to promote flowering in Arabidopsis thaliana.Plant cell reports · 2025Article
- STEMIN transcription factor drives selective chromatin remodeling for gene activation within a relaxed chromatin during reprogramming in the moss Physcomitrium patens.The Plant journal : for cell and molecular biology · 2025Article
- Genome-Wide Reidentification and Expression Analysis ofInternational journal of molecular sciences · 2025Article
- Transcriptome Analysis Reveals Sugar and Hormone Signaling Pathways Mediating Flower Induction in Pitaya (International journal of molecular sciences · 2025Article
- Small molecules and heat treatments reverse vernalization via epigenetic modification in Arabidopsis.Communications biology · 2025Article
- Carbon and nitrogen signaling regulate FLOWERING LOCUS C and impact flowering time in Arabidopsis.Plant physiology · 2024Article
- Gene and Its Promoter Cloning, and Functional Validation ofInternational journal of molecular sciences · 2024Article
- Article
- Genome-wide identification of a MADS-box transcription factor family and their expression during floral development in Coptis teeta wall.BMC plant biology · 2024Article
- A novel strategy to map a locus associated with flowering time in canola (Brassica napus L.).Molecular genetics and genomics : MGG · 2024Article
- The CUL3A-LFH1-UBC15 ubiquitin ligase complex mediates SHORT VEGETATIVE PHASE degradation to accelerate flowering at high ambient temperature.Plant communications · 2024Article
- Gene pyramiding for boosted plant growth and broad abiotic stress tolerance.Plant biotechnology journal · 2024Article
- A transcriptomic time-series reveals differing trajectories during pre-floral development in the apex and leaf in winter and spring varieties of Brassica napus.Scientific reports · 2024Article
133 more citing papers are in PubMed but not listed here.
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5 authors.
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Abstract
Flowering in Arabidopsis is controlled by endogenous and environmental signals relayed by distinct genetic pathways. The MADS-box flowering-time gene SOC1 is regulated by several pathways and is proposed to co-ordinate responses to environmental signals. SOC1 is directly activated by CONSTANS (CO) in long photoperiods and is repressed by FLC, a component of the vernalization (low-temperature) pathway. We show that in transgenic plants overexpressing CO and FLC, these proteins regulate flowering time antagonistically and FLC blocks transcriptional activation of SOC1 by CO. A series of SOC1::GUS reporter genes identified a 351 bp promoter sequence that mediates activation by CO and repression by FLC. A CArG box (MADS-domain protein binding element) within this sequence was recognized specifically by FLC in vitro and mediated repression by FLC in vivo, suggesting that FLC binds directly to the SOC1 promoter. We propose that CO is recruited to a separate promoter element by a DNA-binding factor and that activation by CO is impaired when FLC is bound to an adjacent CArG motif.
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