ArticleJournal of virology2002
Decelerating decay of latently infected cells during prolonged therapy for human immunodeficiency virus type 1 infection.
Article in Journal of virology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 36 citations in OpenAlex.
- Predictions of time to HIV viral rebound following ART suspension that incorporate personal biomarkers.PLoS computational biology · 2019Article
- Quantifying the turnover of transcriptional subclasses of HIV-1-infected cells.PLoS computational biology · 2014Article
- A stochastic model of latently infected cell reactivation and viral blip generation in treated HIV patients.PLoS computational biology · 2011Article
- Intracellular transactivation of HIV can account for the decelerating decay of virus load during drug therapy.Molecular systems biology · 2010Article
- Modeling latently infected cell activation: viral and latent reservoir persistence, and viral blips in HIV-infected patients on potent therapy.PLoS computational biology · 2009Article
- Modeling HIV persistence, the latent reservoir, and viral blips.Journal of theoretical biology · 2009Review
- Constraints on the dominant mechanism for HIV viral dynamics in patients on raltegravir.Antiviral therapy · 2009Article
- Asymmetric division of activated latently infected cells may explain the decay kinetics of the HIV-1 latent reservoir and intermittent viral blips.Mathematical biosciences · 2009Article
- Low-level HIV-1 replication and the dynamics of the resting CD4+ T cell reservoir for HIV-1 in the setting of HAART.BMC infectious diseases · 2008Article
- Viral and latent reservoir persistence in HIV-1-infected patients on therapy.PLoS computational biology · 2006Article
- Heterogeneous clearance rates of long-lived lymphocytes infected with HIV: intrinsic stability predicts lifelong persistence.Proceedings of the National Academy of Sciences of the United States of America · 2003Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antiviral therapy induces a rapid drop in human immunodeficiency virus type 1 viremia, but the decline of virus levels decelerates over time. Mathematical modeling demonstrates that the source of residual virus production might be a single compartment of latently infected cells with an extended distribution of activation rates.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.