Evidence map›Paper›PMID 12162453›Full record

ReviewMolecular and cellular biochemistry

Measurements in vivo of parameters pertinent to ROS/RNS using EPR spectroscopy.

Nadeem Khan, Harold Swartz

Abstract readReview
PubMed
In one paragraph

Review in Molecular and cellular biochemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Triarylmethyl Radicals: EPR Study ofZeitschrift fur physikalische Chemie (Frankfurt am Main, Germany) · 2017
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Hyperfine interactions of narrow-line trityl radical with solvent molecules.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2013
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Esterified trityl radicals as intracellular oxygen probes.Free radical biology & medicine · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nadeem KhanEPR Center, Department of Diagnostic Radiology, Dartmouth Medical School, Hanover, NH 03755, USA.
Harold Swartz

Funding

USE OF SOLUBLE TRITYL SPIN PROBES FOR EPR OXIMETRY INVESTIGATIONSP41RR011602 · NCRR · DARTMOUTH COLLEGE · PI SWARTZ, HAROLD M · 1996 to 2002
$1.7M
NCRR NIH HHS P41 RR11602
6 · The paper itself

Abstract

The technique of in vivo EPR spectroscopy can provide useful and even unique information pertinent to the study of oxygen/ nitrogen radicals and related processes. The parameters that can be measured include: (a) Oxygen centered radicals (by spin trapping); (b) carbon centered radicals (by spin trapping and sometimes by direct observation); (c) sulfur centered radicals (by spin trapping and sometimes by direct observation); (d) nitric oxide (by spin trapping); (e) oxygen (using oxygen sensitive paramagnetic materials); (f) redox state (using metabolism of nitroxides); (g) thiol groups (using special nitroxides); (h) pH (using special nitroxides); (h) perfusion (using washout of paramagnetic tracers); (i) some redox active metal ions (chromium, manganese). The current state of the art for these and other measurements is discussed, especially in relationship to experiments that are likely to be useful for studies of reactive oxygen species (ROS) and/or reactive nitrogen species (RNS).

Indexed as

AnimalsCarbonCellsElectron Spin Resonance SpectroscopyFree RadicalsHumansHydrogen-Ion ConcentrationReactive Nitrogen SpeciesReactive Oxygen SpeciesSpin TrappingSulfhydryl CompoundsSulfurCarbonFree RadicalsReactive Nitrogen SpeciesReactive Oxygen SpeciesSulfhydryl CompoundsSulfur

Identifiers

PMID12162453

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.