ReviewMolecular and cellular biochemistry
Cytokine polymorphisms in silicosis and other pneumoconioses.
Review in Molecular and cellular biochemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
20 citing papers in PubMed, 53 citations in OpenAlex.
- The emerging roles of microRNAs in pneumoconiosis: pathogenic mechanisms and clinical implications.Frontiers in cell and developmental biology · 2026Review
- Cytokine Profiles as Predictive Biomarkers of Disease Severity and Progression in Engineered Stone Silicosis: A Machine Learning Approach.Diagnostics (Basel, Switzerland) · 2025Article
- Effects of Green Tea Polyphenol Epigallocatechin-3-Gallate on Markers of Inflammation and Fibrosis in a Rat Model of Pulmonary Silicosis.International journal of molecular sciences · 2023Article
- Biomonitoring Exposure and Early Diagnosis in Silicosis: A Comprehensive Review of the Current Literature.Biomedicines · 2022Review
- Tetracycline ameliorates silica-induced pulmonary inflammation and fibrosis via inhibition of caspase-1.Respiratory research · 2022Article
- Genome-wide analysis of aberrantly expressed microRNAs in bronchoalveolar lavage fluid from patients with silicosis.Industrial health · 2016Article
- Roles of microRNA-146a and microRNA-181b in regulating the secretion of tumor necrosis factor-α and interleukin-1β in silicon dioxide-induced NR8383 rat macrophages.Molecular medicine reports · 2015Article
- Gene-environment interaction from international cohorts: impact on development and evolution of occupational and environmental lung and airway disease.Seminars in respiratory and critical care medicine · 2015Review
- Pneumoconiosis increases the risk of peripheral arterial disease: a nationwide population-based study.Medicine · 2015Article
- The alarmin IL-1α is a master cytokine in acute lung inflammation induced by silica micro- and nanoparticles.Particle and fibre toxicology · 2014Article
- Pesticides, chemical and industrial exposures in relation to systemic lupus erythematosus.Lupus · 2014Review
- Dust events, pulmonary diseases and immune system.American journal of clinical and experimental immunology · 2014Review
- Molecular Evaluation of the IFN γ +874, TNF α -308, and IL-1Ra VNTR Sequences in Silicosis.Maedica · 2012Article
- Autoantibodies in silicosis patients and in silica-exposed individuals.Rheumatology international · 2010Article
- IL-1beta differently involved in IL-8 and FGF-2 release in crystalline silica-treated lung cell co-cultures.Particle and fibre toxicology · 2008Article
- Silica binding and toxicity in alveolar macrophages.Free radical biology & medicine · 2008Review
- Gene-environment interactions in the development of complex disease phenotypes.International journal of environmental research and public health · 2008Article
- T-889C IL-1alpha promoter polymorphism influences the response to oral cyclophosphamide in scleroderma patients with alveolitis.Clinical rheumatology · 2007Article
- Polymorphism in clinical immunology - From HLA typing to immunogenetic profiling.Journal of translational medicine · 2003Article
- Induction of chemokines by low-dose intratracheal silica is reduced in TNFR I (p55) null mice.Toxicological sciences : an official journal of the Society of Toxicology · 2003Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Silicosis and coal workers' pneumoconiosis are complex multifactorial lung diseases whose etiopathogenesis are not well defined. It is generally accepted that fibrotic lung disorders are mediated by macrophage-derived cytokines and growth factors. There is evidence showing a crucial role for tumor necrosis factor-a (TNF-alpha) and interleukin-1 (IL-1) in inflammation caused by silica dust and in the transition from simple to progressive massive fibrosis. In this review we discuss genetic polymorphisms responsible for regulating the production of these proinflammatory cytokines and their role in modifying silicosis severity.
Indexed as
Identifiers
12162437W2105786130What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.