ReviewThorax2002
Chronic obstructive pulmonary disease. 1: Susceptibility factors for COPD the genotype-environment interaction.
Review in Thorax, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
37 citing papers in PubMed, 5 syntheses or guidelines pooled it, 150 citations in OpenAlex.
- Pooled it
- Pooled it
- Association of IREB2 Gene rs2568494 Polymorphism with Risk of Chronic Obstructive Pulmonary Disease: A Meta-Analysis.Medical science monitor : international medical journal of experimental and clinical research · 2016Pooled it
- Glutathione S-transferase M1 and T1 gene polymorphism and COPD risk in smokers: an updated analysis.Molecular biology reports · 2012Pooled it
- TNF-308 gene polymorphism is associated with COPD risk among Asians: meta-analysis of data for 6,118 subjects.Molecular biology reports · 2011Pooled it
- Aquaporin 5 polymorphisms and rate of lung function decline in chronic obstructive pulmonary disease.PloS one · 2010Trial
- Prolastin, a pharmaceutical preparation of purified human alpha1-antitrypsin, blocks endotoxin-mediated cytokine release.Respiratory research · 2005Trial
- Article
- Article
- Asthma-COPD overlap: current understanding and the utility of experimental models.European respiratory review : an official journal of the European Respiratory Society · 2021Review
- Observational
- Testing gene-environment interactions for rare and/or common variants in sequencing association studies.PloS one · 2020Article
- Test Gene-Environment Interactions for Multiple Traits in Sequencing Association Studies.Human heredity · 2019Article
- In vitro modeling of COPD inflammation and limitation of p38 inhibitor - SB203580.International journal of chronic obstructive pulmonary disease · 2016Article
- Associations of ABHD2 genetic variations with risks for chronic obstructive pulmonary disease in a Chinese Han population.PloS one · 2015Article
- Increased risk of radiographic emphysema in HIV is associated with elevated soluble CD14 and nadir CD4.Chest · 2014Article
- Association between β2-Adrenergic Receptor-16Arg/Gly Gene Polymorphism and Chronic Obstructive Pulmonary Disease Risk:Systematic Review and Meta-Analysis.Iranian journal of public health · 2014Review
- Trimethoprim-sulfamethoxazole treatment does not reverse obstructive pulmonary changes in pneumocystis-colonized nonhuman primates with SHIV infection.Journal of acquired immune deficiency syndromes (1999) · 2014Article
- Expression of aquaporins in bronchial tissue and lung parenchyma of patients with chronic obstructive pulmonary disease.Multidisciplinary respiratory medicine · 2014Article
- Human immunodeficiency virus-associated obstructive lung diseases.Clinics in chest medicine · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Genetic factors including alpha(1)-antitrypsin deficiency are important in COPD. Candidate gene association studies in COPD are reviewed. Efforts to identify interactions between genetic factors and environmental determinants such as smoking may lead to improved understanding of the pathogenesis of the disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.