Evidence map›Paper›PMID 12149347›Full record

ArticleJournal of clinical microbiology2002

External quality assessment program for Chlamydia trachomatis diagnostic testing by nucleic acid amplification assays.

Sally Land, Sepehr Tabrizi, Anthony Gust, Elizabeth Johnson, Susan Garland, Elizabeth M Dax

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sally LandNational Serology Reference Laboratory, Australia, St Vincent's Institute of Medical Research, Fitzroy, VIC 3065, Australia. sally@nrl.gov.au
Sepehr Tabrizi
Anthony Gust
Elizabeth Johnson
Susan Garland
Elizabeth M Dax
St Vincents Institute of Medical Research · AURoyal Women's Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the results from 57 Australian diagnostic laboratories testing two external quality assessment panels using either the Roche Amplicor Chlamydia trachomatis test (R-PCR) or the Abbott LCx Chlamydia trachomatis assay (A-ligase chain reaction [LCR]). Panel samples were either normal urine spiked with Chlamydia trachomatis antigen or clinical urine specimens. There was no significant difference between laboratories or between assays in detection of C. trachomatis-positive clinical samples. Only at the lower limit of detection of the assays did the R-PCR demonstrate increased sensitivity over the A-LCR in the detection of C. trachomatis antigen. However, it was found that single-sample testing could lead to decreased test sensitivity. Detection of the presence of inhibitors of nucleic acid amplification differed between laboratories.

Indexed as

Reagent Kits, DiagnosticAustraliaChlamydia InfectionsChlamydia trachomatisHumansLaboratoriesLigase Chain ReactionNucleic Acid Amplification TechniquesPolymerase Chain ReactionQuality ControlSensitivity and SpecificityUrineReagent Kits, Diagnostic

Identifiers

PMID12149347
PMCPMC120684
OpenAlexW2145208666

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.