ArticleJournal of clinical microbiology2002
Issues associated with and recommendations for using PCR to detect outbreaks of pertussis.
Article in Journal of clinical microbiology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- Durability of protection after 5 doses of acellular pertussis vaccine among 5-9 year old children in King County, Washington.Vaccine · 2021Article
- Association of Diphtheria-Tetanus-Acellular Pertussis Vaccine Timeliness and Number of Doses With Age-Specific Pertussis Risk in Infants and Young Children.JAMA network open · 2021Article
- AsymptomaticeLife · 2021Observational
- AsymptomaticmedRxiv : the preprint server for health sciences · 2020Article
- Challenges and clinical relevance of molecular detection of Bordetella pertussis in South Africa.BMC infectious diseases · 2019Article
- Pertussis outbreak in Polish shooters with adverse event analysis.Biology of sport · 2017Article
- Laboratory Diagnosis of Pertussis.Clinical microbiology reviews · 2015Review
- Harmonization of Bordetella pertussis real-time PCR diagnostics in the United States in 2012.Journal of clinical microbiology · 2015Article
- Diagnosis of pertussis using nasopharyngeal IgA and polymerase chain reaction in specimens from outpatients in Australia.European journal of microbiology & immunology · 2014Article
- Estimation of the underlying burden of pertussis in adolescents and adults in Southern Ontario, Canada.PloS one · 2013Article
- Towards improved accuracy of Bordetella pertussis nucleic acid amplification tests.Journal of clinical microbiology · 2012Review
- Aerosolized vaccine as an unexpected source of false-positive Bordetella pertussis PCR results.Journal of clinical microbiology · 2012Article
- Novel multitarget real-time PCR assay for rapid detection of Bordetella species in clinical specimens.Journal of clinical microbiology · 2011Article
- Pertussis resurgence in Toronto, Canada: a population-based study including test-incidence feedback modeling.BMC public health · 2011Article
- Recommendation for the use of newly introduced Tdap vaccine in Korea.Korean journal of pediatrics · 2011Article
- Improved selective isolation of Bordetella pertussis by use of modified cyclodextrin solid medium.Journal of clinical microbiology · 2009Article
- Article
- Identification and evaluation of new target sequences for specific detection of Bordetella pertussis by real-time PCR.Journal of clinical microbiology · 2008Article
- Pertussis vaccination for health care workers.Clinical microbiology reviews · 2008Review
- Noninvasive ventilation for patients near the end of life: what do we know and what do we need to know?Critical care medicine · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Two outbreaks of respiratory tract illness associated with prolonged cough occurring in 1998 and 1999 in New York State were investigated. A PCR test for Bordetella pertussis was primarily used by a private laboratory to confirm 680 pertussis cases. Several clinical specimens had positive culture results for B. pertussis during both outbreaks, which confirmed that B. pertussis was circulating during the outbreaks. However, testing by the New York State Department of Health reference laboratory suggested that some of the PCR results may have been falsely positive. In addition, features of the outbreak that suggested that B. pertussis may not have been the primary agent of infection included a low attack rate among incompletely vaccinated children and a significant amount of illness among patients testing PCR negative for B. pertussis. These investigations highlight the importance of appropriate clinical laboratory quality assurance programs, of the limitations of the PCR test, and of interpreting laboratory results in context of clinical disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.