ArticleCanadian journal of veterinary research = Revue canadienne de recherche veterinaire2002
Identification of subpopulations of bovine mammary-gland phagocytes and evaluation of sensitivity and specificity of morphologic and functional indicators of bovine mastitis.
Article in Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
7 citing papers in PubMed, 22 citations in OpenAlex.
- Transcriptome Profiling of mInternational journal of molecular sciences · 2021Article
- A Paradox in Bacterial Pathogenesis: Activation of the Local Macrophage Inflammasome Is Required for Virulence ofPathogens (Basel, Switzerland) · 2020Article
- Factors Affecting the Patterns of Total Amount and Proportions of Leukocytes in Bovine Milk.Animals : an open access journal from MDPI · 2020Article
- Effect of intramammary infusion of recombinant bovine GM-CSF and IL-8 on CMT score, somatic cell count, and milk mononuclear cell populations in Holstein cows with Staphylococcus aureus subclinical mastitis.Veterinary research communications · 2017Article
- Decrease in bovine CD14 positive cells in colostrum is associated with the incidence of mastitis after calving.Veterinary research communications · 2010Article
- Multifactorial relationships between intramammary invasion by Staphylococcus aureus and bovine leukocyte markers.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2007Article
- Relationships between the phagocytic ability of milk macrophages and polymorphonuclear cells and somatic cell counts in uninfected cows.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2006Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The number and function of bovine mammary-gland phagocytes were assessed in 8 lactating cows, each tested at least twice within an 8-mo period (total number of observations, 20). Macrophages and polymorphonuclear (PMN) cells were evaluated by conventional cytology, flow cytometry, fluorescent microscopy, and somatic-cell count (SCC). Phagocytosis was evaluated from the uptake of fluorescent beads and expressed as median fluorescence intensity (MFI). Two major subpopulations of phagocytes, of low or high MFI (LFI or HFI), were observed, and there were up to 4 sub-subpopulations within the HFI subpopulation of both macrophages and PMN cells. Fluorescent microscopy identified phagocytes containing up to 4 beads per cell. Cows showing < or = 72.3% phagocytes by cytology were regarded as non-mastitic (11 observations), and those showing > or = 80.7% phagocytes were considered to be mastitic (8 observations). Phagocyte MFI was negatively associated with mastitis; that is, the higher the MFI, the lower the SCC. The percentage of HFI PMN cells was the only indicator of mastitis with 100% sensitivity and specificity. Thus, bovine mammary-gland phagocytes consist of several subpopulations of different phagocytic ability, whose assessment more adequately predicts bovine mastitis than do morphologic indicators.
Indexed as
Identifiers
12146888PMC227000W2265904532What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.