Evidence map›Paper›PMID 12145751›Full record

ArticleAmerican journal of human genetics2002

A genetic landscape reshaped by recent events: Y-chromosomal insights into central Asia.

Tatiana Zerjal, R Spencer Wells, Nadira Yuldasheva, Ruslan Ruzibakiev, Chris Tyler-Smith

Abstract read
In one paragraph

Article in American journal of human genetics, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Ancestral Origins and Admixture History of Kazakhs.Molecular biology and evolution · 2024
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  18. Dispersals of the Siberian Y-chromosome haplogroup Q in Eurasia.Molecular genetics and genomics : MGG · 2018
    Article
  19. Article
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tatiana ZerjalDepartment of Biochemistry, University of Oxford, Oxford, OX1 3QU, United Kingdom.
R Spencer Wells
Nadira Yuldasheva
Ruslan Ruzibakiev
Chris Tyler-Smith

Funding

Wellcome Trust
6 · The paper itself

Abstract

Sixteen Y-chromosomal microsatellites and 16 binary markers have been used to analyze DNA variation in 408 male subjects from 15 populations in Central Asia. Large genetic differences were found between populations, but these did not display an obvious geographical or linguistic pattern like that usually seen for Y-chromosomal variation. Nevertheless, an underlying east-west clinal pattern could be detected by the Autocorrelation Index for DNA Analysis and admixture analysis, and this pattern was interpreted as being derived from the ancient peopling of the area, reinforced by subsequent migrations. Two particularly striking features were seen: an extremely high level of Y-chromosomal differentiation between geographically close populations, accompanied by low diversity within some populations. These were due to the presence of high-frequency population-specific lineages and suggested the occurrence of several recent bottlenecks or founder events. Such events could account for the lack of a clear overall pattern and emphasize the importance of multiple recent events in reshaping this genetic landscape.

Indexed as

PhylogenyAsia, CentralEmigration and ImmigrationGene FrequencyGenetic VariationGeographyHaplotypesHumansLinguisticsMaleMicrosatellite RepeatsPolymorphism, GeneticY Chromosome

Identifiers

PMID12145751
PMCPMC419996

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.