Evidence map›Paper›PMID 12142309›Full record

ArticleBMJ (Clinical research ed.)2002

Resource implications and health benefits of primary prevention strategies for cardiovascular disease in people aged 30 to 74: mathematical modelling study.

Tom Marshall, Andrew Rouse

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in BMJ (Clinical research ed.), 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
19.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 57 citations in OpenAlex.

  1. Targeted case finding in the prevention of cardiovascular disease: a stepped wedge cluster randomised controlled trial.The British journal of general practice : the journal of the Royal College of General Practitioners · 2016 · on this map
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  6. Cost effectiveness of case-finding strategies for primary prevention of cardiovascular disease: a modelling study.The British journal of general practice : the journal of the Royal College of General Practitioners · 2017
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  12. A simple risk score using routine data for predicting cardiovascular disease in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2010
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  18. The use of cardiovascular risk factor information in practice databases: making the best of patient data.The British journal of general practice : the journal of the Royal College of General Practitioners · 2006
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tom MarshallPublic Health and Epidemiology, University of Birmingham, Birmingham B15 2TT. T.P.Marshall@bham.ac.uk
Andrew Rouse
University of Birmingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo develop a model to determine resource costs and health benefits of implementing guidelines for the prevention of cardiovascular disease in primary care.

designModelling of data from six strategies for prevention of cardiovascular disease. Strategies incorporated two ways of identifying patients for assessment: traditional (assessment of all adults) and novel (preselection of patients for assessment using a prior estimate of their risk of cardiovascular disease). Three treatment strategies were modelled in conjunction with each identification strategy.

settingEngland. SUBJECTS: Patients aged 30 to 74 eligible for primary prevention strategies for cardiovascular disease who were selected from a hypothetical population of 2000.

main outcome measuresResource costs of assessing eligible adults, providing treatment and follow up to those eligible, and number of cardiovascular events this should prevent.

resultsNovel strategies prevented more cardiovascular disease, at lower cost, than traditional strategies. Some treatment strategies prevent more cardiovascular disease with fewer resources than others. The findings were robust across a range of different assumptions about workload.

conclusionPreselecting patients for assessment makes better use of staff time than assessing all adults. Treating many patients with low cost drugs is more efficient than prescribing a few patients intensive antihypertensives and statins. Authors of guidelines should model workload implications and health benefits of following their recommendations.

Indexed as

Health Care CostsModels, EconometricAdultAgedCardiovascular DiseasesComputer SimulationCost-Benefit AnalysisEnglandHumansMiddle AgedPatient SelectionPrimary Health CarePrimary PreventionRisk AssessmentSensitivity and SpecificityTreatment Outcome

Identifiers

PMID12142309
PMCPMC117452
OpenAlexW2121560357

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.