ArticleGenetics2002
Chromosomal elements evolve at different rates in the Drosophila genome.
Article in Genetics, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Muller "Elements" inGenetics · 2018Article
- Inversion evolutionary rates might limit the experimental identification of inversion breakpoints in non-model species.Scientific reports · 2017Article
- Genomics of parallel adaptation at two timescales in Drosophila.PLoS genetics · 2017Article
- Dense gene physical maps of the non-model species Drosophila subobscura.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2017Article
- Genomic composition and evolution of Aedes aegypti chromosomes revealed by the analysis of physically mapped supercontigs.BMC biology · 2014Article
- Testing chromosomal phylogenies and inversion breakpoint reuse in Drosophila. The martensis cluster revisited.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2011Article
- A physical map for an Asian malaria mosquito, Anopheles stephensi.The American journal of tropical medicine and hygiene · 2010Article
- Article
- FISH mapping of microsatellite loci from Drosophila subobscura and its comparison to related species.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2010Article
- Cloning and sequencing of the breakpoint regions of inversion 5g fixed in Drosophila buzzatii.Chromosoma · 2009Article
- Article
- Independent origins of new sex-linked chromosomes in the melanica and robusta species groups of Drosophila.BMC evolutionary biology · 2008Article
- A BAC-based integrated linkage map of the silkworm Bombyx mori.Genome biology · 2008Article
- Principles of genome evolution in the Drosophila melanogaster species group.PLoS biology · 2007Article
- The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Comparative polytene chromosome maps of D. montana and D. virilis.Chromosoma · 2007Article
- Article
- Evolution of secretin family GPCR members in the metazoa.BMC evolutionary biology · 2006Article
- Rates and patterns of chromosomal evolution in Drosophila pseudoobscura and D. miranda.Genetics · 2006Article
- A genomic comparison of faster-sex, faster-X, and faster-male evolution between Drosophila melanogaster and Drosophila pseudoobscura.Journal of molecular evolution · 2006Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent results indicate that the rate of chromosomal rearrangement in the genus Drosophila is the highest found so far in any eukaryote. This conclusion is based chiefly on the comparative mapping analysis of a single chromosomal element (Muller's element E) in two species, D. melanogaster and D. repleta, representing the two farthest lineages within the genus (the Sophophora and Drosophila subgenera, respectively). We have extended the analysis to two other chromosomal elements (Muller's elements A and D) and tested for differences in rate of evolution among chromosomes. With this purpose, detailed physical maps of chromosomes X and 4 of D. repleta were constructed by in situ hybridization of 145 DNA probes (gene clones, cosmids, and P1 phages) and their gene arrangements compared with those of the homologous chromosomes X and 3L of D. melanogaster. Both chromosomal elements have been extensively reshuffled over their entire length. The number of paracentric inversions fixed has been estimated as 118 +/- 17 for element A and 56 +/- 8 for element D. Comparison with previous data for elements E and B shows that there are fourfold differences in evolution rate among chromosomal elements, with chromosome X exhibiting the highest rate of rearrangement. Combining all results, we estimated that 393 paracentric inversions have been fixed in the whole genome since the divergence between D. repleta and D. melanogaster. This amounts to an average rate of 0.053 disruptions/Mb/myr, corroborating the high rate of rearrangement in the genus Drosophila.
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