ReviewCurrent rheumatology reports2002
Adult growth hormone deficiency in patients with fibromyalgia.
Review in Current rheumatology reports, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed.
- [Treatment of fibromyalgia syndrome with gamma-hydroxybutyrate : A randomized controlled study].Schmerz (Berlin, Germany) · 2017Trial
- Benefits of resistance exercise in lean women with fibromyalgia: involvement of IGF-1 and leptin.BMC musculoskeletal disorders · 2017Trial
- Acute effects of physical exercise on the serum insulin-like growth factor system in women with fibromyalgia.BMC musculoskeletal disorders · 2017Trial
- Resistance exercise improves muscle strength, health status and pain intensity in fibromyalgia--a randomized controlled trial.Arthritis research & therapy · 2015Trial
- Exercise and obesity in fibromyalgia: beneficial roles of IGF-1 and resistin?Arthritis research & therapy · 2013Trial
- Changes in pain and insulin-like growth factor 1 in fibromyalgia during exercise: the involvement of cerebrospinal inflammatory factors and neuropeptides.Arthritis research & therapy · 2012Trial
- A six-month randomized controlled trial of exercise and pyridostigmine in the treatment of fibromyalgia.Arthritis and rheumatism · 2008Trial
- Identifying microRNAs Possibly Implicated in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and Fibromyalgia: A Review.International journal of molecular sciences · 2024Review
- Metabolic and quality of life effects of growth hormone replacement in patients with TBI and AGHD: A pilot study.Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society · 2023Observational
- Stress-associated weight gain, fibromyalgia symptoms, cardiometabolic markers, and human growth hormone suppression respond to an amino acid supplement blend: Results of a prospective, cohort study.Frontiers in endocrinology · 2023Observational
- The Link Between Empty Sella Syndrome, Fibromyalgia, and Chronic Fatigue Syndrome: The Role of Increased Cerebrospinal Fluid Pressure.Journal of pain research · 2023Review
- Possible Molecular Mediators Involved and Mechanistic Insight into Fibromyalgia and Associated Co-morbidities.Neurochemical research · 2019Review
- Controlled, cross-sectional, multi-center study of physical capacity and associated factors in women with fibromyalgia.BMC musculoskeletal disorders · 2018Article
- Decrease of Serum IGF-1 Level is Not Associated With Obstructive Sleep Apnea in Fibromyalgia Patients.Archives of rheumatology · 2017Article
- Work Ability in Fibromyalgia: An Update in the 21st Century.Current rheumatology reviews · 2017Review
- Profile of circulating microRNAs in fibromyalgia and their relation to symptom severity: an exploratory study.Rheumatology international · 2015Article
- Growth hormone and cognitive function.Nature reviews. Endocrinology · 2013Review
- Profile of cerebrospinal microRNAs in fibromyalgia.PloS one · 2013Article
- [Fibromyalgia].Zeitschrift fur Rheumatologie · 2011Review
- Pain catastrophizing and salivary cortisol responses to laboratory pain testing in temporomandibular disorder and healthy participants.The journal of pain · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adult growth hormone (GH) deficiency is a well-described clinical syndrome with many features reminiscent of fibromyalgia. There is evidence that GH deficiency as defined in terms of a low insulin-like growth factor-1 (IGF-1) level occurs in approximately 30% of patients with fibromyalgia and is probably the cause of some morbidity. It seems most likely that impaired GH secretion in fibromyalgia is related to a physiologic dysregulation of the hypothalamic-pituitary-adrenal axis (HPA) with a resulting increase in hypothalamic somatostatin tone. It is postulated that impaired GH secretion is secondary to chronic physical and psychological stressors. It appears that impaired GH secretion is more common than clinically significant GH deficiency with low IGF-1 levels. The severe GH deficiency that occurs in a subset of patients with fibromyalgia is of clinical relevance because it is a treatable disorder with demonstrated benefits to patients.
Indexed as
Identifiers
12126582What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.