Evidence map›Paper›PMID 12121963›Full record

ArticleAntimicrobial agents and chemotherapy2002

In vitro susceptibilities of zygomycetes to combinations of antimicrobial agents.

Eric Dannaoui, Javier Afeltra, Jacques F G M Meis, Paul E Verweij, Eurofung Network

Open access · greenAbstract readComparative Study
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 77 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Improved In Vitro Anti-Journal of fungi (Basel, Switzerland) · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Drug combinations against Mucor irregularis in vitro.Antimicrobial agents and chemotherapy · 2013
    Article
  14. Article
  15. Rhino-orbital-cerebral mucormycosis.Current infectious disease reports · 2012
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Eric DannaouiDepartment of Medical Microbiology, University Medical Center St. Radboud, 6500 HB Nijmegen, The Netherlands.
Javier Afeltra
Jacques F G M Meis
Paul E Verweij
Eurofung Network
University Medical Center · USCanisius-Wilhelmina Ziekenhuis · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Combinations of antimicrobial agents were tested against 35 strains of zygomycetes. The interaction between amphotericin B and rifampin was synergistic or additive. Flucytosine alone was inactive and, upon combination with amphotericin B, synergy was not achieved. The combination of amphotericin B with terbinafine was synergistic for 20% of strains, and the interaction between terbinafine and voriconazole was synergistic for 44% of strains. Antagonism was not observed.

Indexed as

Amphotericin BAntifungal AgentsDrug CombinationsDrug SynergismMicrobial Sensitivity TestsMucoralesZygomycosisAmphotericin BAntifungal AgentsDrug Combinations

Identifiers

PMID12121963
PMCPMC127328
OpenAlexW2138700198

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.