ArticleThe Plant cell2002
Missense mutation in the PAS2 domain of phytochrome A impairs subnuclear localization and a subset of responses.
Article in The Plant cell, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed, 70 citations in OpenAlex.
- A cis-regulatory element of the PHYTOCHROME A gene confers the submergence escape capacity for amphibious plants.Nature communications · 2025Article
- Two Distinct Molecular Types of Phytochrome A in Plants: Evidence of Existence and Implications for Functioning.International journal of molecular sciences · 2023Review
- Arabidopsis FIN219/JAR1 interacts with phytochrome A under far-red light and jasmonates in regulating hypocotyl elongation via a functional demand manner.PLoS genetics · 2023Article
- Phytochrome A in plants comprises two structurally and functionally distinct populations - water-soluble phyA' and amphiphilic phyA″.Biophysical reviews · 2022Review
- From the archives: Where the light goes; flower color, chloroplast transport, and phytochrome A.The Plant cell · 2022Article
- Lysine 206 in Arabidopsis phytochrome A is the major site for ubiquitin-dependent protein degradation.Journal of biochemistry · 2016Article
- Light-activated phytochrome A and B interact with members of the SPA family to promote photomorphogenesis in Arabidopsis by reorganizing the COP1/SPA complex.The Plant cell · 2015Article
- In response to partial plant shading, the lack of phytochrome A does not directly induce leaf senescence but alters the fine-tuning of chlorophyll biosynthesis.Journal of experimental botany · 2014Article
- Missense mutation in the amino terminus of phytochrome A disrupts the nuclear import of the photoreceptor.Plant physiology · 2012Article
- A novel high-throughput in vivo molecular screen for shade avoidance mutants identifies a novel phyA mutation.Journal of experimental botany · 2011Article
- Bell-like homeodomain selectively regulates the high-irradiance response of phytochrome A.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- The histidine kinase-related domain of Arabidopsis phytochrome a controls the spectral sensitivity and the subcellular distribution of the photoreceptor.Plant physiology · 2009Article
- Phytochrome A mediates rapid red light-induced phosphorylation of Arabidopsis FAR-RED ELONGATED HYPOCOTYL1 in a low fluence response.The Plant cell · 2009Article
- Detection of spatial-specific phytochrome responses using targeted expression of biliverdin reductase in Arabidopsis.Plant physiology · 2009Article
- Phytochrome-mediated light signaling in plants: emerging trends.Physiology and molecular biology of plants : an international journal of functional plant biology · 2008Article
- Blue Rhythms Between GIGANTEA and Phytochromes.Plant signaling & behavior · 2007Article
- GIGANTEA regulates phytochrome A-mediated photomorphogenesis independently of its role in the circadian clock.Plant physiology · 2007Article
- The serine-rich N-terminal region of Arabidopsis phytochrome A is required for protein stability.Plant molecular biology · 2007Article
- Insights into nuclear organization in plants as revealed by the dynamic distribution of Arabidopsis SR splicing factors.The Plant cell · 2006Article
- Combining experimental and predicted datasets for determination of the subcellular location of proteins in Arabidopsis.Plant physiology · 2005Article
Corrections and comments
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Authors and funding
11 authors at 7 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Phytochrome A signaling shows two photobiologically discrete outputs: so-called very-low-fluence responses (VLFR) and high-irradiance responses (HIR). By modifying previous screening protocols, we isolated two Arabidopsis mutants retaining VLFR and lacking HIR. Phytochrome A negatively or positively regulates phytochrome B signaling, depending on light conditions. These mutants retained the negative but lacked the positive regulation. Both mutants carry the novel phyA-302 allele, in which Glu-777 (a residue conserved in angiosperm phytochromes) changed to Lys in the PAS2 motif of the C-terminal domain. The phyA-302 mutants showed a 50% reduction in phytochrome A levels in darkness, but this difference was compensated for by greater stability under continuous far-red light. phyA-302:green fluorescent protein fusion proteins showed normal translocation from the cytosol to the nucleus under continuous far-red light but failed to produce nuclear spots, suggesting that nuclear speckles could be involved in HIR signaling and phytochrome A degradation. We propose that the PAS2 domain of phytochrome A is necessary to initiate signaling in HIR but not in VLFR, likely via interaction with a specific partner.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.