ArticleJAMA2002
Failure of estrogen plus progestin therapy for prevention.
Article in JAMA, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00000611 (Women's Health Initiative), which is not on this map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Women's Health Initiative (WHI)
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 211 citations in OpenAlex.
- Hormone replacement therapy for preventing cardiovascular disease in post-menopausal women.The Cochrane database of systematic reviews · 2005Pooled it
- Hormone replacement therapy after surgery for stage 1 or 2 cutaneous melanoma.British journal of cancer · 2004Trial
- Escitalopram reduces hot flashes in nondepressed menopausal women: A pilot study.Annals of clinical psychiatry : official journal of the American Academy of Clinical PsychiatristsTrial
- Cardiac ventricular Kir6.1 ATP-sensitive potassium channels: an overlooked effector of cardioprotection.Frontiers in physiology · 2026Article
- Hormones and thrombosis: the dark side of the moon.Blood transfusion = Trasfusione del sangue · 2024Review
- Epidemiology and Risk Factors for Breast Cancer: 21st Century Advances, Gaps to Address through Interdisciplinary Science.Cold Spring Harbor perspectives in medicine · 2023Review
- Sex Difference in OA: Should We Blame Estrogen?European journal of rheumatology · 2023Article
- The impact of 17β-estradiol on the estrogen-deficient female brain: from mechanisms to therapy with hot flushes as target symptoms.Frontiers in endocrinology · 2023Review
- Ceritinib (LDK378) prevents bone lossFrontiers in endocrinology · 2022Article
- Estrogen therapy for osteoporosis in the modern era.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018Review
- Effect of hormone replacement therapy on cardiac autonomic modulation.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2014Article
- Article
- Physician differences in managing postmenopausal osteoporosis: results from the POSSIBLE US™ treatment registry study.Drugs & aging · 2011Article
- Persistence and switching patterns among women with varied osteoporosis medication histories: 12-month results from POSSIBLE US.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2010Article
- New evidence rekindles the hormone therapy debate.The journal of family planning and reproductive health care · 2010Article
- Potential mechanisms of estrogen quinone carcinogenesis.Chemical research in toxicology · 2008Review
- Ligand-modified aminobisphosphonate for linking proteins to hydroxyapatite and bone surface.Bioconjugate chemistry · 2008Article
- A critique of Women's Health Initiative Studies (2002-2006).Nuclear receptor signaling · 2006Article
- Estrogen-induced contraction of coronary arteries is mediated by superoxide generated in vascular smooth muscle.American journal of physiology. Heart and circulatory physiology · 2005Article
- Validation of a decision model for preventive pharmacological strategies in postmenopausal women.European journal of epidemiology · 2005Article
Corrections and comments
- Comment on
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.