ArticleEndocrine pathology1996
Overview of Neuroendocrine Cells and Tumors.
Article in Endocrine pathology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 21 citations in OpenAlex.
- First Report on a Rare Poorly Differentiated Neuroendocrine Tumour of the External Auditory Canal Involving Pinna.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Pulmonary Neuroendocrine Neoplasms Overexpressing Epithelial-Mesenchymal Transition Mechanical Barriers Genes Lack Immune-Suppressive Response and Present an Increased Risk of Metastasis.Frontiers in oncology · 2021Article
- Small cell neuroendocrine carcinoma of nose and paranasal sinuses: a study of three cases with short review of the literature.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2009Article
- C-cell hyperplasia and medullary thyroid microcarcinoma.Endocrine pathology · 2001Review
- Insulin and Glucagon mRNA Expression and Prohormone Convertase Immunoreactivity in Normal and Neoplastic Pancreatic Endocrine Tissue.Endocrine pathology · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The diffuse neuroendocrine system (DNES) is composed of cells and tumors with secretory granules ranging from 50-400 nm in diameter. Members of the DNES commonly stain for chromogranin and synaptophysin by immunohistochemistry and may express a variety of peptide hormones. Recent studies have shown that the proprotein convertases (proconvertases or PCs) are good broad-spectrum markers for members of the DNES. Gene expression can be readily detecting in neuroendocrine cells and tumors by in situ hybridization (ISH). Newer techniques such as in situ polymerase chain reaction (PCR) can be used to detect gene products that are expressed in low copy numbers in neuroendocrine cells. The concept of multidirectional differentiation is an important notion that helps to explain multiple patterns of phenotypic expression observed in some neuroendocrine tumors.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.