Evidence map›Paper›PMID 12114753›Full record

ArticleEndocrine pathology2002

Medullary thyroid carcinoma, follicular variant.

Mehtap Cakir, Hasan Altunbas, Mustafa Kemal Balci, Umit Karayalcin, Gulten Karpuzoglu

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Endocrine pathology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Histopathology of C Cells and Medullary Thyroid Carcinoma.Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2025
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Mehtap CakirAkdeniz University, Faculty of Medicine, Division of Endocrinology and Metabolism, Antalya, Turkey.
Hasan Altunbas
Mustafa Kemal Balci
Umit Karayalcin
Gulten Karpuzoglu
Akdeniz University · TRAntalya IVF · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report here a 48-yr-old woman presenting with a solitary thyroid nodule in the left lobe of the thyroid. The aspiration cytology of the nodule was reported as follicular neoplasia and she underwent surgery. Frozen section was suspicious for medullary thyroid carcinoma and a total thyroidectomy was performed. The pathology report revealed medullary thyroid carcinoma, follicular variant. Immunohistochemical analysis was negative for thyroglobulin and positive for calcitonin. A few patients with this variant have been reported in the literature, mainly diagnosed by immunohistochemical features of the tumor. In light of the limited information we have obtained from the literature, it is reasonable to emphasize that these cases should be distinguished from the mixed medullary- follicular thyroid carcinomas and medullary carcinomas with entrapped follicles. Immunohistochemical examination with calcitonin and thyroglobulin is also essential.

Indexed as

Adenocarcinoma, FollicularBiopsy, NeedleCalcitoninCarcinoma, MedullaryChromogranin AChromograninsDiagnosis, DifferentialFemaleHumansImmunohistochemistryMiddle AgedThyroglobulinThyroid NeoplasmsCalcitoninChromogranin AChromograninsThyroglobulin

Identifiers

PMID12114753
OpenAlexW2057821328

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.