ArticleEndocrine pathology2002
Simultaneous medullary and papillary microcarcinoma of thyroid in a patient with secondary hyperparathyroidism.
Article in Endocrine pathology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Simultaneous Occurrence of Medullary Thyroid Carcinoma and Papillary Thyroid Carcinoma: A Case Series with Literature Review.Current oncology (Toronto, Ont.) · 2023Review
- Epidemiology of Simultaneous Medullary and Papillary Thyroid Carcinomas (MTC/PTC): An Italian Multicenter Study.Cancers · 2019Article
- Synchronous occurrence of medullary and papillary carcinoma of the thyroid in a patient with cutaneous melanoma: determination of BRAFV600E in peripheral blood and tissues. Report of a case and review of the literature.Endocrine pathology · 2014Review
- Increased incidence of papillary thyroid microcarcinoma with decreased tumor size of thyroid cancer.Medical oncology (Northwood, London, England) · 2010Article
- Composite metastatic carcinoma in lymph nodes of patients with concurrent medullary and papillary thyroid carcinoma: a report of two cases.Endocrine pathology · 2004Article
Corrections and comments
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Authors and funding
3 authors.
Funding
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Abstract
The simultaneous occurrence of two neoplasms of different cellular origin in one organ is a known but rare event. Such a situation occurs in the thyroid when medullary and follicular carcinoma with differentiation develops. Several cases of transitional tumors have been reported, but the simultaneous occurrence of a carcinoma with medullary and follicular differentiated carcinoma is rare. In all patients, tumors were suspected after local examination of the thyroid. We report on a patient in whom a papillary microcarcinoma was detected on the left side and a medullary carcinoma on the right side while the patient was undergoing surgery for secondary hyperparathyroidism. Both tumors were confirmed by immunohistology; regional lymph nodes were free of tumor. Although the simultaneous occurrence of papillary and medullary carcinoma may have been a simple coincidence, the patient's history offers room for further speculation; he had chronic replicative hepatitis C and a 13-yr history of immunosuppression following renal transplantation. Therefore, a common oncogenic stimulus may have been involved. In the final analysis, the reason for both malignancies could not be clearly established.
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Registered trials
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