ArticleEndocrine pathology1998
Primitive Neuroectodermal Tumor of the Meninges: An Histological, Immunohistochemical, Ultrastructural, and Cytogenetic Study.
Article in Endocrine pathology, 1998. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- What's in a name? Intracranial peripheral primitive neuroectodermal tumors and CNS primitive neuroectodermal tumors are not the same.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2013Pooled it
- Diagnosis, treatment, and postoperative follow-up of intracranial Ewing sarcoma (EWS): a case report.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- Primary intracranial peripheral primitive neuroectodermal tumor: lessons from an exceptionally rare neoplasm. Illustrative case.Journal of neurosurgery. Case lessons · 2024Article
- Primary Intracranial Ewing Sarcoma WithBrain tumor research and treatment · 2023Article
- Case report: Primary intracranial EWs/PNET in adults: Clinical experience and literature review.Frontiers in oncology · 2022Article
- Primary intracranial Ewing sarcoma/ peripheral primitive neuroectodermal tumor, an entity of unacquaintance: a series of 8 cases.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021Article
- Primary intracranial extraosseous Ewing's sarcoma.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019Article
- Synthetic treatment of intracranial peripheral primitive neuroectodermal tumor with multiple metastasis: a case report.OncoTargets and therapy · 2016Article
- Primary intracranial Ewing's sarcoma with unusual features.International journal of clinical and experimental pathology · 2015Article
- [Shoulder girdle, AC and SC joints].Operative Orthopadie und Traumatologie · 2014Article
- Primary extraosseous intracranial Ewing's sarcoma: Case report and literature review.Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology · 2011Article
- Central nervous system extraosseous Ewing sarcoma: radiologic manifestations of this newly defined pathologic entity.AJNR. American journal of neuroradiology · 2006Review
- Intracranial Ewing sarcoma/'peripheral' primitive neuroectodermal tumor of dural origin with molecular genetic confirmation.Journal of neuro-oncology · 2001Article
- Primary intracranial dural-based Ewing sarcoma/peripheral primitive neuroectodermal tumor mimicking a meningioma: A rare tumor with review of literature.Asian journal of neurosurgeryReview
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report a case of primitive neuroectodermal tumor (PNET) arising from the meninges in a 30-yr-old female patient whose clinical and radiological features were consistent with meningioma. The neoplasm was composed of primitive small, round cells, growing in sheets and nests in continuity with meningeal layers. Ultrastructurally, the neoplastic cells were characterized by large and regular nuclei, primitive cytoplasm with pools of glycogen, and lack of dense core granules. The neuroectodermal nature of the tumor was confirmed by positive immunostaining for vimentin, neurofilaments, neuron specific enolase (NSE), and 013 (an antibody raised against MIC2 antigen). Further support to the diagnosis was obtained by reverse transcriptase-polymerase chain reaction (RT-PCR) detection of Chromogranin A and Secretogranin II genes. t(1 1;22) translocation was also observed by RT-PCR, a finding that was not recorded in previously described intracranial PNET. The tumor followed a malignant course, recurring and spreading to chest wall and sacroiliac region over a 10-yr period. The meningeal location enlarges the topographic spectrum of intracranial PNET, and this tumor has to be considered in the differential diagnosis with meningioma.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.