ArticleNature2002
Sequence and analysis of chromosome 2 of Dictyostelium discoideum.
Article in Nature, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
71 citing papers in PubMed, 194 citations in OpenAlex.
- IqgD is a Rac1-interacting IQGAP required for efficient growth of Dictyostelium discoideum on bacterial lawns.Cell communication and signaling : CCS · 2026Article
- Heterologous expression of MfWRKY40 enhanced drought resistance of alfalfa.BMC plant biology · 2026Article
- Hypermutable hotspot enables the rapid evolution of self/non-self recognition genes inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Article
- Convergent pairs of highly transcribed genes restrict chromatin looping in Dictyostelium discoideum.Nucleic acids research · 2025Article
- WRKY transcription factors participate in abiotic stress responses mediated by sugar metabolism.Frontiers in plant science · 2025Review
- Genome-Wide Identification, Evolutionary and Functional Analyses of WRKY Family Members inGenes · 2023Article
- Genome-Wide Analysis of Members of the WRKY Gene Family and Their Cold Stress Response in Prunus mume.Genes · 2019Article
- The Maize WRKY Transcription Factor ZmWRKY40 Confers Drought Resistance in TransgenicInternational journal of molecular sciences · 2018Article
- A moso bamboo WRKY gene PeWRKY83 confers salinity tolerance in transgenic Arabidopsis plants.Scientific reports · 2017Article
- Adenylyl cyclase mRNA localizes to the posterior of polarized DICTYOSTELIUM cells during chemotaxis.BMC cell biology · 2017Article
- Gene Structures, Evolution and Transcriptional Profiling of the WRKY Gene Family in Castor Bean (Ricinus communis L.).PloS one · 2016Article
- Genome-wide investigation and transcriptome analysis of the WRKY gene family in Gossypium.Molecular genetics and genomics : MGG · 2015Article
- Molecular cloning and characterization of a group II WRKY transcription factor from Jatropha curcas, an important biofuel crop.DNA and cell biology · 2014Article
- The WRKY Transcription Factor Genes in Lotus japonicus.International journal of genomics · 2014Article
- Matricellular signal transduction involving calmodulin in the social amoebozoan dictyostelium.Genes · 2013Article
- Pharmacogenetics of resistance to Cisplatin and other anticancer drugs and the role of sphingolipid metabolism.Methods in molecular biology (Clifton, N.J.) · 2013Article
- A matricellular protein and EGF-like repeat signalling in the social amoebozoan Dictyostelium discoideum.Cellular and molecular life sciences : CMLS · 2012Review
- Article
- Phylogeny-wide analysis of social amoeba genomes highlights ancient origins for complex intercellular communication.Genome research · 2011Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
19 authors at 14 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The genome of the lower eukaryote Dictyostelium discoideum comprises six chromosomes. Here we report the sequence of the largest, chromosome 2, which at 8 megabases (Mb) represents about 25% of the genome. Despite an A + T content of nearly 80%, the chromosome codes for 2,799 predicted protein coding genes and 73 transfer RNA genes. This gene density, about 1 gene per 2.6 kilobases (kb), is surpassed only by Saccharomyces cerevisiae (one per 2 kb) and is similar to that of Schizosaccharomyces pombe (one per 2.5 kb). If we assume that the other chromosomes have a similar gene density, we can expect around 11,000 genes in the D. discoideum genome. A significant number of the genes show higher similarities to genes of vertebrates than to those of other fully sequenced eukaryotes. This analysis strengthens the view that the evolutionary position of D. discoideum is located before the branching of metazoa and fungi but after the divergence of the plant kingdom, placing it close to the base of metazoan evolution.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.