ArticleThe Journal of physiology2002
Fast network oscillations induced by potassium transients in the rat hippocampus in vitro.
Article in The Journal of physiology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed, 94 citations in OpenAlex.
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- Transcranial alternating current stimulation (tACS) at gamma frequency: an up-and-coming tool to modify the progression of Alzheimer's Disease.Translational neurodegeneration · 2024Review
- Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity.The Journal of cell biology · 2024Article
- Mediation of Sinusoidal Network Oscillations in the Locus Coeruleus of Newborn Rat Slices by Pharmacologically Distinct AMPA and KA Receptors.Brain sciences · 2022Article
- Membrane electrical properties of mouse hippocampal CA1 pyramidal neurons during strong inputs.Biophysical journal · 2022Article
- Phase-locked closed-loop ultrasound stimulation modulates theta and gamma rhythms in the mouse hippocampus.Frontiers in neuroscience · 2022Article
- Biophysical Model: A Promising Method in the Study of the Mechanism of Propofol: A Narrative Review.Computational intelligence and neuroscience · 2022Review
- Activity-mediated accumulation of potassium induces a switch in firing pattern and neuronal excitability type.PLoS computational biology · 2021Article
- Interstitial ions: A key regulator of state-dependent neural activity?Progress in neurobiology · 2020Review
- Generating Brain Waves, the Power of Astrocytes.Frontiers in neuroscience · 2019Review
- The influence of depolarization block on seizure-like activity in networks of excitatory and inhibitory neurons.Journal of computational neuroscience · 2017Article
- The oscillation-like activity in bullfrog ON-OFF retinal ganglion cell.Cognitive neurodynamics · 2016Article
- Reduced Efficacy of the KCC2 Cotransporter Promotes Epileptic Oscillations in a Subiculum Network Model.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Snapshots of the Brain in Action: Local Circuit Operations through the Lens of γ Oscillations.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Intrinsic Cornu Ammonis Area 1 Theta-Nested Gamma Oscillations Induced by Optogenetic Theta Frequency Stimulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Inhibition of propofol anesthesia on functional connectivity between LFPs in PFC during rat working memory task.PloS one · 2013Article
- The role of glutamatergic inputs onto parvalbumin-positive interneurons: relevance for schizophrenia.Reviews in the neurosciences · 2012Review
- Glutamate receptor subtypes mediating synaptic activation of prefrontal cortex neurons: relevance for schizophrenia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Synchrony with shunting inhibition in a feedforward inhibitory network.Journal of computational neuroscience · 2010Article
- Searching for autocoherence in the cortical network with a time-frequency analysis of the local field potential.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
Brief pressure ejection of solutions containing potassium, caesium or rubidium ions into stratum radiatum of the CA1 or CA3 regions of the hippocampal slice evoked a fast network oscillation. The activity evoked lasted approximately 3-25 s with the predominant frequency component being in the gamma frequency range (30-80 Hz), although beta frequency (15-30 Hz) and ultrafast (> 80 Hz) components could also be seen. The gamma frequency component of the oscillation remained constant, even when large changes in power occurred, and was synchronous across the CA1 region. Measurements with potassium ion-sensitive electrodes revealed that the network oscillation was accompanied by increases (0.5 to 2.0 mM) in the extracellular potassium concentration [K+]o. Bath application of the N-methyl-D-aspartate (NMDA) receptor antagonists D(-)-2-amino-5-phosphonopentanoic acid (D-AP5; 50 microM) had no significant effect but the alpha-amino-3-hydroxy-5-methyl-4-isooxazolepropionic acid (AMPA)/kainate receptor antagonist 2,3,-dioxo-6-nitro-1,2,3,4-tetrahydrobenzo[f]quinoxaline-7-sulphonamide disodium (NBQX; 20 microM) caused a significant reduction (86.7 +/- 4.5 %) in the power in the gamma frequency range. Residual rhythmic activity, presumably arising in the interneuronal network, was blocked by the GABA(A) receptor antagonist bicuculline. The putative gap junction blocker octanol caused a decrease in the power of the gamma frequency component of 75.5 +/- 5.6 %, while carbenoxolone produced a reduction of only 14 +/- 42 %. These experiments demonstrate that a modest increase in exogenous [K+]o in the hippocampus in vitro is sufficient to evoke a fast network oscillation, which is an emergent property of the synaptically and electrically interconnected neuronal network.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.