Evidence map›Paper›PMID 12092479›Full record

GuidelineInfectious disease clinics of North America2002

Molecular methods for diagnosis of infective endocarditis.

Gorm Lisby, Ernö Gutschik, David T Durack

Abstract readGuidelinePractice GuidelineReview
In one paragraph

Guideline in Infectious disease clinics of North America, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Guideline
  3. Uncommon pathogens causing infective endocarditis.Indian journal of thoracic and cardiovascular surgery · 2024
    Review
  4. Observational
  5. Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Heart valves should not be routinely cultured.Journal of clinical microbiology · 2008
    Article
  11. Review
  12. Infective endocarditis.BMJ (Clinical research ed.) · 2006
    Review
  13. An evaluation of extended incubation time with blind subculture of blood cultures in patients with suspected endocarditis.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2006
    Article
  14. Molecular Methods in the Diagnosis of Endocarditis.Current infectious disease reports · 2004
    Article
  15. Review
  16. Review
  17. Infective Endocarditis in Elderly Patients.Current infectious disease reports · 2003
    Article
  18. Article
  19. Diagnosis of infective endocarditis.BMJ (Clinical research ed.) · 2002
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Gorm LisbyDepartment of Clinical Microbiology, Hvidovre Hospital, University of Copenhagen, Kettegårds Alle 30, 2650 Hvidovre, Denmark.
Ernö Gutschik
David T Durack

Funding

Biofilm Architecture of Subgingival PlaqueR03DE018424 · NIDCR · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LUX, RENATE, MOTER, ANNETTE · 2008 to 2009
$145k
NIDCR NIH HHS R03 DE018424
6 · The paper itself

Abstract

The culture of viable microorganisms from the blood or from cardiac tissue is currently the most important test for diagnosis of IE. This is followed by phenotypic identification methods used for taxonomic positioning of isolates. However, in those cases where the invading microorganism is difficult or impossible to culture (including instances of prior antimicrobial treatment), molecular methods provide the best means for detection. Molecular identification methods, either nucleic acid target or signal amplification alone or in combination with sequence analysis can offer a more specific and in some cases a more rapid alternative to the phenotypic methods. We propose revised Duke criteria of IE, including positive identification of an organism by molecular biology methods.

Indexed as

Culture MediaEndocarditisEndocarditis, BacterialFungiHumansMolecular Diagnostic TechniquesMolecular Probe TechniquesMycosesNucleic Acid Amplification TechniquesPolymerase Chain ReactionSensitivity and SpecificitySerologic TestsCulture Media

Identifiers

PMID12092479
PMCPMC2928072

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.