Evidence map›Paper›PMID 12089290›Full record

ArticleJournal of clinical microbiology2002

Virulence genes in Helicobacter pylori strains from West Bengal residents with overt H. pylori-associated disease and healthy volunteers.

Santanu Chattopadhyay, Simanti Datta, Abhijit Chowdhury, Sujit Chowdhury, Asish K Mukhopadhyay, K Rajendran, S K Bhattacharya, Douglas E Berg, G Balakrish Nair

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Allelic Variation ofMicroorganisms · 2025
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  6. Frontiers in microbiology · 2021
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  7. Journal of biosciences · 2020
    Review
  8. Article
  9. Observational
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  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. The association of vacA genotypes and Helicobacter pylori-related gastroduodenal diseases in the Middle East.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2009
    Article
  19. Article
  20. Prevalence of virulence-associated genotypes of Helicobacter pylori and correlation with severity of gastric pathology in patients from western Sicily, Italy.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Santanu ChattopadhyayNational Institute of Cholera and Enteric Diseases, Calcutta, India.
Simanti Datta
Abhijit Chowdhury
Sujit Chowdhury
Asish K Mukhopadhyay
K Rajendran
S K Bhattacharya
Douglas E Berg
G Balakrish Nair

Funding

Washington University DDRCC Supplemental Equipment RequestP30DK052574 · NIDDK · WASHINGTON UNIVERSITY · PI Nicholas O. Davidson · 2000 to 2026
$30.8M
H. PYLORI INFECTION AND GI DISEASE IN ALASKA NATIVESR01DK053727 · NIDDK · WASHINGTON UNIVERSITY · PI BERG, DOUGLAS EUGENE · 1999 to 2003
$1.3M
DRUG RESISTANCE AND GENE TRANSFER IN H PYLORIR01AI038166 · NIAID · WASHINGTON UNIVERSITY · PI BERG, DOUGLAS EUGENE · 1995 to 2003
$1.1M
Molecular Genetics of H. Pylori In IndiaR03AI049161 · NIAID · WASHINGTON UNIVERSITY · PI BERG, DOUGLAS EUGENE · 2000 to 2002
$222k
NIAID NIH HHS AI 38166NIAID NIH HHS AI49161NIDDK NIH HHS DK53727NIDDK NIH HHS P30 DK052574NIDDK NIH HHS P30DK52574
6 · The paper itself

Abstract

We compared putative molecular markers of virulence (vacA, cagA, and iceA) of Helicobacter pylori strains isolated from 52 adult duodenal ulcer patients from West Bengal, India, with those of H. pylori strains isolated from 48 adult healthy volunteers from the same region. On the basis of genotyping by PCR, we conclude that the H. pylori strains isolated from the two study groups were indistinguishable and that there are geographic variations in the association of certain putative H. pylori virulence genes with clinical status.

Indexed as

Antigens, BacterialGenes, BacterialAdultBacterial Outer Membrane ProteinsBacterial ProteinsCase-Control StudiesDuodenal UlcerFemaleGenotypeHelicobacter InfectionsHelicobacter pyloriHumansIndiaMaleVirulenceAntigens, BacterialBacterial Outer Membrane ProteinsBacterial ProteinscagA protein, Helicobacter pyloriice nucleation proteinVacA protein, Helicobacter pylori

Identifiers

PMID12089290
PMCPMC120544

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.