Evidence map›Paper›PMID 12089257›Full record

ArticleJournal of clinical microbiology2002

Histologic and genotypic characterization of a novel Mycobacterium species found in three cats.

Greg D Appleyard, Edward G Clark

Open access · greenAbstract readCase ReportsComparative Study
In one paragraph

Article in Journal of clinical microbiology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 50 citations in OpenAlex.

  1. SystemicPathogens (Basel, Switzerland) · 2020
    Article
  2. Article
  3. Potential Animal Reservoir ofTropical medicine and infectious disease · 2018
    Review
  4. Article
  5. Observational
  6. Article
  7. Infectious hepatopathies in dogs and cats.Topics in companion animal medicine · 2009
    Review
  8. Localised Mycobacterium ulcerans infection in a cat in Australia.Journal of feline medicine and surgery · 2008
    Article
  9. Article
  10. Article
  11. PCR studies of feline leprosy cases.Journal of feline medicine and surgery · 2004
    Article
  12. Latin grammar headaches.Journal of clinical microbiology · 2003
    Article
  13. Article
  14. Update on molecular techniques for diagnostic testing of infectious disease.The Veterinary clinics of North America. Small animal practice · 2003
    Review
  15. Review
  16. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Greg D AppleyardDepartment of Veterinary Pathology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada S7N 5B4. greg.appleyard@usask.ca
Edward G Clark
Diagnostic Services Manitoba · CAUniversity of Saskatchewan · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three cases of feline atypical mycobacteriosis from different geographical regions in North America were characterized by large clusters of filamentous bacteria visible on hematoxylin-and-eosin-stained tissue sections. PCR amplification demonstrated the presence of Mycobacterium-specific nucleic acid in samples of skin lesions from these cases. PCR-assisted cloning and DNA sequence analysis of a 541-bp length of the Mycobacterium 16S rRNA gene generated DNA sequences which were >95% identical, suggesting that the three isolates were closely related. Two of the sequences were 99% identical and may represent the same species. Alignment with comparable 16S rRNA gene sequences from 66 Mycobacterium species and partially characterized isolates highlighted similarities (>94%) with Mycobacterium bohemicum, Mycobacterium haemophilum, Mycobacterium ulcerans, Mycobacterium avium subsp. avium, and isolate IWGMT 90242. Parsimony analysis of sequence data suggested relatedness to M. leprae. Significant molecular genetic and pathobiological differences between these three similar isolates and other known species of mycobacteria suggested that the organisms may not have been described previously and that these cases may represent a new form of mycobacterial disease in cats. We suggest the term "Mycobacterium visibilis" to describe the organism from which the two nearly identical sequences were obtained.

Indexed as

AnimalsBase SequenceCat DiseasesCatsDNA, BacterialFemaleGenes, BacterialGenotypeMolecular Sequence DataMycobacterium Infections, NontuberculousNontuberculous MycobacteriaPhylogenyPolymerase Chain ReactionRNA, BacterialRNA, Ribosomal, 16SSequence Homology, Nucleic AcidDNA, BacterialRNA, BacterialRNA, Ribosomal, 16S

Identifiers

PMID12089257
PMCPMC120602
OpenAlexW1996676954

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.