Evidence map›Paper›PMID 12084944›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2002

Disease surveillance in recombining pathogens: multilocus genotypes identify sources of human Coccidioides infections.

Matthew C Fisher, Bruce Rannala, Vishnu Chaturvedi, John W Taylor

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Emerging Antifungal Resistance in Fungal Pathogens.Current clinical microbiology reports · 2024
    Review
  6. Review
  7. Article
  8. First Analysis of HumanJournal of fungi (Basel, Switzerland) · 2019
    Article
  9. Article
  10. Coccidioides ecology and genomics.Medical mycology · 2019
    Review
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Genetic structure of Plasmodium falciparum populations between lowland and highland sites and antimalarial drug resistance in Western Kenya.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2009
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthew C FisherThe Institute of Zoology, Regent's Park, London NW1 4RY, United Kingdom. matthew.fisher@ioz.ac.uk
Bruce Rannala
Vishnu Chaturvedi
John W Taylor

Funding

SCREENING FOR C. IMMITIS ANTIGENS BY DNA IMMUNIZATIONP01AI037232 · NIAID · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI KIRKLAND, THEO N · 1995 to 2003
$2.6M
DISEQUILIBRIUM MAPPING OF COMPLEX GENETIC DISEASESR01HG001988 · NHGRI · UNIVERSITY OF CALIFORNIA DAVIS · PI RANNALA, BRUCE · 1999 to 2011
$1.4M
NHGRI NIH HHS R01 HG001988NHGRI NIH HHS R01 HG01988NIAID NIH HHS P01 AI037232NIAID NIH HHS P01 AI37232Wellcome Trust
6 · The paper itself

Abstract

Molecular surveillance of pathogenic microbes works by genotyping isolates with DNA fingerprinting techniques and then using these genotypes to assign individuals to populations. Clonality is assumed in many fingerprinting studies, although this assumption has been shown to be false for many organisms. To accommodate recombining organisms into surveillance programs, methods using population allele frequencies in combination with individual multilocus genotypes are necessary. Here, we develop a statistical method appropriate for haploid recombining microbes that allows individuals to be assigned to populations. We illustrate the usefulness of this technique by inferring the source populations for Coccidioides isolates recovered from patients treated outside the endemic area of Coccidioides sp., the etiological agents of human coccidioidomycosis, but with a travel history including visits to one or more endemic areas.

Indexed as

Population SurveillanceAllelesCoccidioidesCoccidioidomycosisGene FrequencyGenotypeHumans

Identifiers

PMID12084944
PMCPMC124424

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.