Hormonal regulation of the epithelial sodium channel ENaC: N or P(o)?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

28 citing papers in PubMed.

1. Differential Assembly of Native Epithelial Sodium Channel Complexes Across Mouse Epithelial Tissues.Kidney360 · 2026
   Article
2. Differential Assembly of Native ENaC Complexes Across Mouse Epithelial Tissues.bioRxiv : the preprint server for biology · 2026
   Article
3. Thickness of the airway surface liquid layer in the lung is affected in cystic fibrosis by compromised synergistic regulation of the ENaC ion channel.Journal of the Royal Society, Interface · 2019
   Article
4. Connecting tubule glomerular feedback mediates tubuloglomerular feedback resetting after unilateral nephrectomy.American journal of physiology. Renal physiology · 2018
   Article
5. Mineralocorticoid Receptor and Aldosterone-Related Biomarkers of End-Organ Damage in Cardiometabolic Disease.Biomolecules · 2018
   Review
6. Delivery of ENaC siRNA to epithelial cells mediated by a targeted nanocomplex: a therapeutic strategy for cystic fibrosis.Scientific reports · 2017
   Article
7. Feedforward activation of endothelial ENaC by high sodium.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2014
   Article
8. Defective interactions of protein partner with ion channels and transporters as alternative mechanisms of membrane channelopathies.Biochimica et biophysica acta · 2014
   Review
9. Proteases, cystic fibrosis and the epithelial sodium channel (ENaC).Cell and tissue research · 2013
   Review
10. Plasmin and chymotrypsin have distinct preferences for channel activating cleavage sites in the γ subunit of the human epithelial sodium channel.The Journal of general physiology · 2012
    Article
11. Regulation of transport in the connecting tubule and cortical collecting duct.Comprehensive Physiology · 2012
    Review
12. Vasotocin- and mesotocin-induced increases in short-circuit current across tree frog skin.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2011
    Article
13. Regulation of the epithelial sodium channel (ENaC) by membrane trafficking.Biochimica et biophysica acta · 2010
    Review
14. A mutation of the epithelial sodium channel associated with atypical cystic fibrosis increases channel open probability and reduces Na+ self inhibition.The Journal of physiology · 2010
    Article
15. Rac1-mediated NADPH oxidase release of O2- regulates epithelial sodium channel activity in the alveolar epithelium.American journal of physiology. Lung cellular and molecular physiology · 2010
    Article
16. The delta-subunit of the epithelial sodium channel (ENaC) enhances channel activity and alters proteolytic ENaC activation.The Journal of biological chemistry · 2009
    Article
17. Regulated sodium transport in the renal connecting tubule (CNT) via the epithelial sodium channel (ENaC).Pflugers Archiv : European journal of physiology · 2009
    Review
18. Regulation of the epithelial sodium channel by membrane trafficking.American journal of physiology. Renal physiology · 2009
    Review
19. Vasotocin has the potential to inhibit basolateral Na(+)/K (+)-pump current across isolated skin of tree frog in vitro, via its V(2)-type receptor/cAMP pathway.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2008
    Article
20. A synthetic prostone activates apical chloride channels in A6 epithelial cells.American journal of physiology. Gastrointestinal and liver physiology · 2008
    Article

Corrections and comments

• Comment on
  Effects of aldosterone on biosynthesis, traffic, and functional expression of epithelial sodium channels in A6 cells.2002

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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