ArticleThe British journal of ophthalmology2002
Ophthalmopathy in childhood Graves' disease.
Article in The British journal of ophthalmology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 80 citations in OpenAlex.
- 2022 European Thyroid Association Guideline for the management of pediatric Graves' disease.European thyroid journal · 2022Guideline
- ISPAD Clinical Practice Consensus Guidelines 2018: Other complications and associated conditions in children and adolescents with type 1 diabetes.Pediatric diabetes · 2018Guideline
- Thyroid eye disease in paediatric Graves' disease: a case series from the Gulf region with comparison to adults.International ophthalmology · 2026Article
- Clinical Outcomes of Orbital Fat Decompression in Pediatric Thyroid Eye Disease: A Two-Center Retrospective Study.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Eyeball descending identification using MRI-based spatial coordinates in thyroid-associated orbitopathy patients with unilateral upper eyelid retraction.Quantitative imaging in medicine and surgery · 2025Article
- Insulin-like Growth Factor-I Receptor and Thyroid-Associated Ophthalmopathy.Endocrine reviews · 2019Review
- Predictive Factors of Development of Graves' Ophthalmopathy for Patients with Juvenile Graves' Disease.International journal of endocrinology · 2016Article
- Thyroid peroxidase antibody positivity and triiodothyronine levels are associated with pediatric Graves' ophthalmopathy.World journal of pediatrics : WJP · 2014Article
- Article
- Association between age at diagnosis of Graves' disease and variants in genes involved in immune response.PloS one · 2013Article
- Pediatric pulmonary arterial hypertension and hyperthyroidism: a potentially fatal combination.The Journal of clinical endocrinology and metabolism · 2012Article
- Assessment of visual acuity, refraction changes, and proptosis in different ages of patients with thyroid diseases.International journal of endocrinology · 2012Article
- Graves disease with exophtalmia in a two-year old child.Molecular imaging and radionuclide therapy · 2011Article
- Clinical features of pediatric Graves' orbitopathy.International ophthalmology · 2010Article
- Childhood Graves' disease and its ophthalmic complications: some sensitive issues.Journal of endocrinological investigation · 2008Article
- Association between thyroid-stimulating immunoglobulin levels and ocular findings in pediatric patients with Graves disease.Transactions of the American Ophthalmological Society · 2007Article
- Progressive restrictive strabismus acquired in infancy.The British journal of ophthalmology · 2005Article
- Juvenile thyrotoxicosis; can we do better?Archives of disease in childhood · 2004Review
- Graves disease in childhood: a review of the options for diagnosis and treatment.Paediatric drugs · 2003Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo study the ocular manifestations and their severity in children with Graves' disease.
methodsAll patients with Graves' disease having regular follow up in a paediatric endocrine clinic were recruited for the study. A comprehensive ophthalmic assessment including ocular motility, exophthalmometry, intraocular pressure (IOP), slit lamp, and fundus examinations was performed.
results83 patients (72 female, 11 male) aged 16 years or below were examined. All are Chinese. Ocular symptoms occurred in 12 patients. Ocular signs of ophthalmopathy were documented in 52 patients (62.7%). Most of them presented with eyelid abnormalities such as lid oedema, lid lag, and lagophthalmos, whereas lower lid retraction was the commonest clinical sign noted (38.6%). Diffuse conjunctival injection was found in four patients (4.8%). 10 patients (12.0%) had mild proptosis of less than 3 mm. Only one patient (1.2%) had limited extraocular motility in extreme gaze. Punctate epithelial corneal erosions were reported in 11 patients (13.3%).
conclusionsThis is the largest series on the ocular complications of childhood Graves' disease in the literature. Although 52 patients (62.7%) were identified with positive ocular changes, none of them had visual threatening complications or debilitating myopathy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.