ArticleJournal of virology2002
Species-specific receptor recognition by a minor-group human rhinovirus (HRV): HRV serotype 1A distinguishes between the murine and the human low-density lipoprotein receptor.
Article in Journal of virology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 33 citations in OpenAlex.
- Human Stimulator of Interferon Genes Promotes Rhinovirus C Replication in Mouse Cells In Vitro and In Vivo.Viruses · 2024Article
- Rhinovirus C Infection Induces Type 2 Innate Lymphoid Cell Expansion and Eosinophilic Airway Inflammation.Frontiers in immunology · 2021Article
- Rhinovirus Attributes that Contribute to Asthma Development.Immunology and allergy clinics of North America · 2019Review
- Review
- A reversible haploid mouse embryonic stem cell biobank resource for functional genomics.Nature · 2017Article
- Viral entry pathways: the example of common cold viruses.Wiener medizinische Wochenschrift (1946) · 2016Review
- Cellular mRNA decay protein AUF1 negatively regulates enterovirus and human rhinovirus infections.Journal of virology · 2013Article
- Gargling for oral hygiene and the development of fever in childhood: a population study in Japan.Journal of epidemiology · 2012Article
- Human rhinovirus 1B exposure induces phosphatidylinositol 3-kinase-dependent airway inflammation in mice.American journal of respiratory and critical care medicine · 2008Article
- Human rhinovirus type 54 infection via heparan sulfate is less efficient and strictly dependent on low endosomal pH.Journal of virology · 2007Article
- Age-dependent poliovirus replication in the mouse central nervous system is determined by internal ribosome entry site-mediated translation.Journal of virology · 2006Article
- The minor receptor group of human rhinovirus (HRV) includes HRV23 and HRV25, but the presence of a lysine in the VP1 HI loop is not sufficient for receptor binding.Journal of virology · 2005Article
- Identification of the human rhinovirus serotype 1A binding site on the murine low-density lipoprotein receptor by using human-mouse receptor chimeras.Journal of virology · 2004Article
- Human rhinovirus type 2-antibody complexes enter and infect cells via Fc-gamma receptor IIB1.Journal of virology · 2004Article
- Sequence and structure of human rhinoviruses reveal the basis of receptor discrimination.Journal of virology · 2003Article
- Changes in rhinovirus protein 2C allow efficient replication in mouse cells.Journal of virology · 2003Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human rhinoviruses (HRV) of the minor receptor group use several members of the low-density lipoprotein receptor superfamily for cell entry. These proteins are evolutionarily highly conserved throughout species and are almost ubiquitously expressed. Their common building blocks, cysteine-rich ligand binding repeats about 40 amino acids in length, exhibit considerable sequence similarity. Various numbers of these repeats are present in the different receptors. We here demonstrate that HRV type 1A (HRV1A) replicates in mouse cells without adaptation. Furthermore, although closely related to HRV2, it fails to bind to the human low-density lipoprotein receptor but recognizes the murine protein, whereas HRV2 binds equally well to both homologues. This difference went unnoticed due to the presence of other receptors, such as the low-density lipoprotein receptor-related protein, which allow species-independent attachment. The species specificity of HRV1A reported here will aid in defining amino acid residues establishing the contact between the viral surface and the receptor.
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