ArticleHeart (British Cardiac Society)2002
Incremental changes in QRS duration in serial ECGs over time identify high risk elderly patients with heart failure.
Article in Heart (British Cardiac Society), 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 105 citations in OpenAlex.
- Possible role of QRS duration in the right ventricle as a perioperative monitoring parameter for right ventricular function: a prospective cohort analysis in robotic mitral valve surgery.Frontiers in cardiovascular medicine · 2024Article
- Timing of cardiac resynchronization therapy implantation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Article
- Article
- Long-Term Outcomes of Tachycardia-Induced Cardiomyopathy Compared with Idiopathic Dilated Cardiomyopathy.Journal of clinical medicine · 2023Article
- Electrocardiogram findings at the initiation of hemodialysis and types of subsequent cardiovascular events.Hypertension research : official journal of the Japanese Society of Hypertension · 2021Article
- Left Ventricular Contraction Duration Is the Most Powerful Predictor of Cardiac Events in LQTS: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2020Article
- Electrical manipulation of the failing heart.Heart failure reviews · 2018Review
- Prolongation of atrio-ventricular node conduction in a rabbit model of ischaemic cardiomyopathy: Role of fibrosis and connexin remodelling.Journal of molecular and cellular cardiology · 2016Article
- Association between Progressive Intraventricular Conduction Disturbance and Cardiovascular Events.PloS one · 2016Article
- Regression of fragmented QRS complex: a marker of electrical reverse remodeling in cardiac resynchronization therapy.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2015Article
- Epidemiological and evolutionary characteristics of heart failure in patients with left bundle branch block - A Moroccan center-based study.Journal of the Saudi Heart Association · 2015Article
- Prognostic Implication of QRS Variability during Hospitalization in Patients with Acute Decompensated Heart Failure.Korean circulation journal · 2014Article
- Association of QRS duration with left ventricular structure and function and risk of heart failure in middle-aged and older adults: the Multi-Ethnic Study of Atherosclerosis (MESA).European journal of heart failure · 2012Article
- Increasing knowledge and changing views in cardiac resynchronization therapy.Heart failure reviews · 2012Article
- Factors associated with development of prolonged QRS duration over 20 years in healthy young adults: the Coronary Artery Risk Development in Young Adults study.Journal of electrocardiology · 2012Article
- Relationship between mechanical and electrical remodelling in patients with cardiac resynchronization implanted defibrillators.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2011Article
- Plus disease in retinopathy of prematurity: quantitative analysis of vascular change.American journal of ophthalmology · 2010Article
- Relation of QRS width in healthy persons to risk of future permanent pacemaker implantation.The American journal of cardiology · 2010Article
- Article
- Familial aggregation and heritability of electrocardiographic intervals and heart rate in a rural Chinese population.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2009Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo investigate the hypothesis that changes in the ECG over time may be an important and readily available marker of prognostic value in patients with heart failure.
methods112 elderly patients (81 men) with stable heart failure, a mean (SD) age of 73.3 (4.4) years, left ventricular ejection fraction 38 (17)%, and peak oxygen consumption 15.1 (4.7) ml/kg/min had ECG measurements on two occasions a minimum of 12 (5) months apart.
resultsDuring the subsequent follow up period (mean 27 (17) months) 45 patients died. QRS duration (p = 0.001) and heart rate (p = 0.03) at baseline were found by Cox proportional hazard method analysis to predict adverse outcomes in these patients. Of the changes in ECG parameters between the first and second visit, broadening of QRS duration (p = 0.001) predicted mortality. On Kaplan-Meier survival analysis, patients with < 5% change in QRS duration had fewer end points than patients with 5-20% change. A > 20% increase in QRS duration was associated with the worst prognosis. Progressive prolongation of QRS duration correlated closely with deterioration of LV systolic and diastolic function.
conclusionA single measurement of QRS duration has significant prognostic value in elderly patients with heart failure and the increase in QRS duration over time is an even better predictor of adverse out comes.
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